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- W1557550609 abstract "Abstract Baseline sister chromatid exchanges (SCEs) increase as a function of average replicon size in a variety of human and Chinese hamster cell lines. This observation is the basis for a model in which SCEs are generated by errors in the unravelling of daughter double helices by topo isomerases. These errors cause exchanges behind the replication fork, not at the fork as several current models assume. This model also provides an explanation for SCEs induced when residual DNA damage that has been replicated interferes with the normal processes of unravelling the daughter strands." @default.
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- W1557550609 title "Correlations between sister chromatid exchange frequencies and replicon sizes" @default.
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- W1557550609 doi "https://doi.org/10.1016/0014-4827(81)90034-3" @default.
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