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- W1557564568 abstract "Publisher Summary This chapter presents the approaches geared to incorporate the systematic analysis of neuromuscular junction (NMJ) function and potential NMJ modifications into the context of larval crawling behavior. It has been found that after an initial lag-phase, high larval crawling activity resulted in several subsequent phases of experience-dependent synaptic potentiation. Depending on the temporal window of occurrence and the junctional phenotypes observed, four phases of experience-dependent potentiation are defined. These distinct phases of potentiation can be followed from their initial induction (phase-I) and the establishment of functional changes (phase-II), up to their morphological consolidation (phase-III/IV). This sequence defines a temporal hierarchy of mechanisms involved in the use-dependent modification of glutamatergic synapses. The development and plasticity of the Drosophila glutamatergic NMJ have been derived from genetic approaches in which morphological and functional phenotypes are analyzed on malfunction." @default.
- W1557564568 created "2016-06-24" @default.
- W1557564568 creator A5054234383 @default.
- W1557564568 date "2006-01-01" @default.
- W1557564568 modified "2023-09-25" @default.
- W1557564568 title "Experience‐Dependent Potentiation of Larval Neuromuscular Synapses" @default.
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- W1557564568 doi "https://doi.org/10.1016/s0074-7742(06)75014-0" @default.
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