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• W1557572005 endingPage "56" @default.
• W1557572005 startingPage "1" @default.
• W1557572005 abstract "Major modifications in chromatin organization occur in spermatid nuclei, resulting in a high degree of DNA packaging within the spermatozoon head. However, before arrest of transcription during midspermiogenesis, high levels of mRNA are found in round spermatids. Some transcripts are the product of genes expressed ubiquitously, whereas some are generated from male germ cell–specific gene homologs of somatic cell genes. Others are transcript variants derived from genes with expression regulated in a testis-specific fashion. The haploid genome of spermatids also initiates the transcription of testis-specific genes. Various general transcription factors, distinct promoter elements, and specific transcription factors are involved in transcriptional regulation. After meiosis, spermatids are genetically but not phenotypically different, because of transcript and protein sharing through cytoplasmic bridges connecting spermatids of the same generation. Interestingly, different types of mRNAs accumulate in the sperm cell nucleus, raising the question of their origin and of a possible role after fertilization." @default.
• W1557572005 created "2016-06-24" @default.
• W1557572005 creator A5031075871 @default.
• W1557572005 creator A5059520747 @default.
• W1557572005 creator A5091869371 @default.
• W1557572005 date "2004-01-01" @default.
• W1557572005 modified "2023-09-23" @default.
• W1557572005 title "Transcription in Haploid Male Germ Cells" @default.
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