FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1558000979> ?p ?o ?g. }

• W1558000979 endingPage "409" @default.
• W1558000979 startingPage "401" @default.
• W1558000979 abstract "A polymicrobial infection comprising subgingival biofilms is the trigger for the chronic immunoinflammatory lesions of periodontitis. These microbial biofilms interface with host immune cells that increase with progressing disease and could result in HIV reactivation in HIV-1-infected patients. Previous reports have focused on the ability of monospecies challenge of macrophages and dendritic cells to detail molecular aspects of their detection and signalling pathways. This study provides a seminal description of the responses of macrophages and dendritic cells to a polybacterial challenge using various oral bacteria as prototype stimuli to examine these response characteristics. The investigation employed a model of HIV-promoter activation and reactivation of HIV viral replication. Oral Gram-negative bacteria elicited significantly greater levels of HIV promoter activation and viral replication from all cell types, compared with Gram-positive bacteria. Selected combinations of oral Gram-negative bacteria elicited synergistic HIV promoter activation and viral replication in macrophages and immature dendritic cells. In mature dendritic cells, there was no synergism in HIV promoter activation and viral replication. Gram-positive bacteria showed no synergism in any cell model. These findings support the importance of determining the characteristics and impact of polybacterial challenges on immune cells to clarify the potential immune recognition and antigen processing that can occur in the oral cavity." @default.
• W1558000979 created "2016-06-24" @default.
• W1558000979 creator A5013096129 @default.
• W1558000979 creator A5062762799 @default.
• W1558000979 creator A5069778200 @default.
• W1558000979 creator A5072889689 @default.
• W1558000979 date "2010-11-12" @default.
• W1558000979 modified "2023-10-16" @default.
• W1558000979 title "Polybacterial challenge enhances HIV reactivation in latently infected macrophages and dendritic cells" @default.
• W1558000979 cites W1534496719 @default.
• W1558000979 cites W1969040248 @default.
• W1558000979 cites W1977945339 @default.
• W1558000979 cites W1985498297 @default.
• W1558000979 cites W1986718102 @default.
• W1558000979 cites W1990517851 @default.
• W1558000979 cites W1999086552 @default.
• W1558000979 cites W2019094601 @default.
• W1558000979 cites W2027298939 @default.
• W1558000979 cites W2045264957 @default.
• W1558000979 cites W2049970827 @default.
• W1558000979 cites W2062813847 @default.
• W1558000979 cites W2082605258 @default.
• W1558000979 cites W2084202098 @default.
• W1558000979 cites W2086463098 @default.
• W1558000979 cites W2091137325 @default.
• W1558000979 cites W2095566926 @default.
• W1558000979 cites W2098008759 @default.
• W1558000979 cites W2099370842 @default.
• W1558000979 cites W2102001108 @default.
• W1558000979 cites W2105214091 @default.
• W1558000979 cites W2111583179 @default.
• W1558000979 cites W2121748291 @default.
• W1558000979 cites W2123937142 @default.
• W1558000979 cites W2132062260 @default.
• W1558000979 cites W2133970739 @default.
• W1558000979 cites W2139962100 @default.
• W1558000979 cites W2142410030 @default.
• W1558000979 cites W2144345929 @default.
• W1558000979 cites W2144914258 @default.
• W1558000979 cites W2147515256 @default.
• W1558000979 cites W2155675552 @default.
• W1558000979 cites W2156433667 @default.
• W1558000979 cites W2157107389 @default.
• W1558000979 cites W2163591292 @default.
• W1558000979 cites W4231311323 @default.
• W1558000979 cites W4313344754 @default.
• W1558000979 doi "https://doi.org/10.1111/j.1365-2567.2010.03375.x" @default.
• W1558000979 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3044906" @default.
• W1558000979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21073452" @default.
• W1558000979 hasPublicationYear "2010" @default.
• W1558000979 type Work @default.
• W1558000979 sameAs 1558000979 @default.
• W1558000979 citedByCount "16" @default.
• W1558000979 countsByYear W15580009792012 @default.
• W1558000979 countsByYear W15580009792013 @default.
• W1558000979 countsByYear W15580009792014 @default.
• W1558000979 countsByYear W15580009792015 @default.
• W1558000979 countsByYear W15580009792016 @default.
• W1558000979 countsByYear W15580009792017 @default.
• W1558000979 countsByYear W15580009792019 @default.
• W1558000979 countsByYear W15580009792020 @default.
• W1558000979 countsByYear W15580009792021 @default.
• W1558000979 crossrefType "journal-article" @default.
• W1558000979 hasAuthorship W1558000979A5013096129 @default.
• W1558000979 hasAuthorship W1558000979A5062762799 @default.
• W1558000979 hasAuthorship W1558000979A5069778200 @default.
• W1558000979 hasAuthorship W1558000979A5072889689 @default.
• W1558000979 hasBestOaLocation W15580009792 @default.
• W1558000979 hasConcept C140704245 @default.
• W1558000979 hasConcept C159047783 @default.
• W1558000979 hasConcept C203014093 @default.
• W1558000979 hasConcept C2522874641 @default.
• W1558000979 hasConcept C2778170410 @default.
• W1558000979 hasConcept C523546767 @default.
• W1558000979 hasConcept C54355233 @default.
• W1558000979 hasConcept C58123911 @default.
• W1558000979 hasConcept C86803240 @default.
• W1558000979 hasConcept C8891405 @default.
• W1558000979 hasConcept C89423630 @default.
• W1558000979 hasConceptScore W1558000979C140704245 @default.
• W1558000979 hasConceptScore W1558000979C159047783 @default.
• W1558000979 hasConceptScore W1558000979C203014093 @default.
• W1558000979 hasConceptScore W1558000979C2522874641 @default.
• W1558000979 hasConceptScore W1558000979C2778170410 @default.
• W1558000979 hasConceptScore W1558000979C523546767 @default.
• W1558000979 hasConceptScore W1558000979C54355233 @default.
• W1558000979 hasConceptScore W1558000979C58123911 @default.
• W1558000979 hasConceptScore W1558000979C86803240 @default.
• W1558000979 hasConceptScore W1558000979C8891405 @default.
• W1558000979 hasConceptScore W1558000979C89423630 @default.
• W1558000979 hasIssue "3" @default.
• W1558000979 hasLocation W15580009791 @default.
• W1558000979 hasLocation W15580009792 @default.
• W1558000979 hasLocation W15580009793 @default.
• W1558000979 hasOpenAccess W1558000979 @default.
• W1558000979 hasPrimaryLocation W15580009791 @default.
• W1558000979 hasRelatedWork W1501404116 @default.
• W1558000979 hasRelatedWork W1972445536 @default.

• next