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- W155829523 abstract "Publisher Summary This chapter examines whether the membrane phenotype of natural killer (NK) cells indicates an independent cell lineage both with regard to ontogenical differentiation and function or whether they belong to an already known cell population, especially the T-cell lineage. The study described in the chapter examined the antisera against brain tissue which were known to react with T cells including mature and immature thymocytes. Anti-asialo GM1 (anti-GA1) reactive with NK cells was found in the antisera against brain tissue. The anti-GA1 antiserum in the presence of complement could selectively eliminate NK activity in vitro and in vivo, but had no effect on cytotoxic T cells, carrier-specific helper T cells, concanavalin A (Con A) reactive T cells, slg-bearing B cells, or LPS reactive lymphocytes. Antigen presenting and accessory cells were not also eliminated by the antiserum. These results indicated that as far as the mature effector cells are examined, GA1 antigen is preferentially expressed on NK cells in adult mice." @default.
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- W155829523 date "1982-01-01" @default.
- W155829523 modified "2023-09-25" @default.
- W155829523 title "CELL LINEAGE OF NK CELL: EVIDENCE FOR T CELL LINEAGE" @default.
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- W155829523 doi "https://doi.org/10.1016/b978-0-12-341360-4.50037-8" @default.
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