FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1558909043> ?p ?o ?g. }

• W1558909043 endingPage "265" @default.
• W1558909043 startingPage "255" @default.
• W1558909043 abstract "Degranulation and membrane fusion by neutrophils are essential to host defense. We sought homologues of neuron-specific fusion proteins in human neutrophils and in their precursors, the promyelocytic cell line HL-60. We screened a differentiated HL-60 library and obtained an 848 bp sequence with a 351 bp open reading frame, identical to that published for human VAMP-2 and including 5' and 3' untranslated regions. RNA from HL-60 cells during differentiation into the neutrophil lineage was subjected to Northern blot analysis. which revealed a transcript of approximately 1050 bp at all stages of differentiation. The amount of these transcripts increased approximately threefold during differentiation, a finding confirmed by quantitative RT-PCR. We also detected mRNA for VAMP-2 in human neutrophils and monocytes using RT-PCR. In like fashion, transcripts of syntaxin-4, another fusion protein, were recovered from a neutrophil cDNA library. As with VAMP-2, expression of syntaxin-4 (determined by Northern blots) also increased, but by only 50%, during differentiation of HL-60 cells. These studies demonstrate that neutrophils and their progenitors possess mRNA for the fusion proteins VAMP-2 and syntaxin-4, and that their transcription increases during differentiation, concurrent with the functional maturation of myeloid cells." @default.
• W1558909043 created "2016-06-24" @default.
• W1558909043 creator A5012294917 @default.
• W1558909043 creator A5033784617 @default.
• W1558909043 creator A5058459641 @default.
• W1558909043 creator A5079714617 @default.
• W1558909043 creator A5089063045 @default.
• W1558909043 date "2001-01-01" @default.
• W1558909043 modified "2023-10-16" @default.
• W1558909043 cites W112630122 @default.
• W1558909043 cites W1499453816 @default.
• W1558909043 cites W1519499074 @default.
• W1558909043 cites W1530469978 @default.
• W1558909043 cites W1547662875 @default.
• W1558909043 cites W1548442754 @default.
• W1558909043 cites W1568376229 @default.
• W1558909043 cites W1576448444 @default.
• W1558909043 cites W1779934359 @default.
• W1558909043 cites W1883920008 @default.
• W1558909043 cites W1952727795 @default.
• W1558909043 cites W1983116402 @default.
• W1558909043 cites W1986587867 @default.
• W1558909043 cites W1987614558 @default.
• W1558909043 cites W1999744850 @default.
• W1558909043 cites W2027775552 @default.
• W1558909043 cites W2028749980 @default.
• W1558909043 cites W2033875319 @default.
• W1558909043 cites W2035354512 @default.
• W1558909043 cites W2043123347 @default.
• W1558909043 cites W2055302296 @default.
• W1558909043 cites W2061045914 @default.
• W1558909043 cites W2073828165 @default.
• W1558909043 cites W2075299978 @default.
• W1558909043 cites W2118828894 @default.
• W1558909043 cites W2125771292 @default.
• W1558909043 cites W2131258235 @default.
• W1558909043 cites W2134812217 @default.
• W1558909043 cites W2167861311 @default.
• W1558909043 cites W2172586216 @default.
• W1558909043 cites W2272968952 @default.
• W1558909043 cites W2320692882 @default.
• W1558909043 cites W2329186577 @default.
• W1558909043 cites W2342443089 @default.
• W1558909043 cites W2395491778 @default.
• W1558909043 cites W2395837037 @default.
• W1558909043 cites W2411423328 @default.
• W1558909043 cites W61342229 @default.
• W1558909043 cites W89675234 @default.
• W1558909043 doi "https://doi.org/10.1023/a:1010903804063" @default.
• W1558909043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11580102" @default.
• W1558909043 hasPublicationYear "2001" @default.
• W1558909043 type Work @default.
• W1558909043 sameAs 1558909043 @default.
• W1558909043 citedByCount "12" @default.
• W1558909043 countsByYear W15589090432015 @default.
• W1558909043 countsByYear W15589090432016 @default.
• W1558909043 crossrefType "journal-article" @default.
• W1558909043 hasAuthorship W1558909043A5012294917 @default.
• W1558909043 hasAuthorship W1558909043A5033784617 @default.
• W1558909043 hasAuthorship W1558909043A5058459641 @default.
• W1558909043 hasAuthorship W1558909043A5079714617 @default.
• W1558909043 hasAuthorship W1558909043A5089063045 @default.
• W1558909043 hasBestOaLocation W15589090432 @default.
• W1558909043 hasConcept C104317684 @default.
• W1558909043 hasConcept C105580179 @default.
• W1558909043 hasConcept C148738053 @default.
• W1558909043 hasConcept C153911025 @default.
• W1558909043 hasConcept C167625842 @default.
• W1558909043 hasConcept C177707886 @default.
• W1558909043 hasConcept C47289529 @default.
• W1558909043 hasConcept C54355233 @default.
• W1558909043 hasConcept C85265743 @default.
• W1558909043 hasConcept C86803240 @default.
• W1558909043 hasConcept C95444343 @default.
• W1558909043 hasConceptScore W1558909043C104317684 @default.
• W1558909043 hasConceptScore W1558909043C105580179 @default.
• W1558909043 hasConceptScore W1558909043C148738053 @default.
• W1558909043 hasConceptScore W1558909043C153911025 @default.
• W1558909043 hasConceptScore W1558909043C167625842 @default.
• W1558909043 hasConceptScore W1558909043C177707886 @default.
• W1558909043 hasConceptScore W1558909043C47289529 @default.
• W1558909043 hasConceptScore W1558909043C54355233 @default.
• W1558909043 hasConceptScore W1558909043C85265743 @default.
• W1558909043 hasConceptScore W1558909043C86803240 @default.
• W1558909043 hasConceptScore W1558909043C95444343 @default.
• W1558909043 hasIssue "4" @default.
• W1558909043 hasLocation W15589090431 @default.
• W1558909043 hasLocation W15589090432 @default.
• W1558909043 hasLocation W15589090433 @default.
• W1558909043 hasOpenAccess W1558909043 @default.
• W1558909043 hasPrimaryLocation W15589090431 @default.
• W1558909043 hasRelatedWork W1966427723 @default.
• W1558909043 hasRelatedWork W1995115362 @default.
• W1558909043 hasRelatedWork W1999620788 @default.
• W1558909043 hasRelatedWork W2013783064 @default.
• W1558909043 hasRelatedWork W2076815804 @default.
• W1558909043 hasRelatedWork W2083535977 @default.
• W1558909043 hasRelatedWork W2093183948 @default.

• next