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• W1559061494 abstract "Abstract Objective To determine whether endothelial nitric oxide synthase (eNOS) polymorphisms confer susceptibility to Behcet’s disease (BD). Methods A meta‐analysis was conducted on the associations between the G894T and 4b/a polymorphisms of eNOS and BD using: (i) the allele contrast, (ii) the recessive model, (iii) the dominant model and (iv) the additive model. Results A total of eight studies, which included 841 cases and 866 controls, were included in the meta‐analysis. Meta‐analysis of the G894T polymorphism revealed no association with BD in all study subjects or in Turkish and Asian populations. However, one Tunisian study of the T allele showed a significant association with BD (OR = 0.707, 95% CI = 0.510–0.980, P = 0.038), but the OR of the T allele among Tunisians was lower, whereas it was higher in Europeans (OR = 2.129, 95% CI = 1.407–3.220, P = 0.0003). Meta‐analysis showed no association between BD and the 4b/a polymorphism in all study subjects. Stratification by ethnicity indicated no significant association between the a allele of the 4b/a polymorphism and BD in Turkish and Asian populations. Conclusions This meta‐analysis shows that the eNOS G894T and the 4b/a polymorphisms are not associated with BD in the Turkish and Asian populations. These data suggest that the G894T and the 4b/a polymorphisms may not confer susceptibility to BD in the Turkish and Asian populations." @default.
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• W1559061494 date "2011-09-29" @default.
• W1559061494 modified "2023-10-17" @default.
• W1559061494 title "Associations between eNOS polymorphisms and susceptibility to Behcet’s disease: a meta-analysis" @default.
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• W1559061494 doi "https://doi.org/10.1111/j.1468-3083.2011.04280.x" @default.
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