FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1559776871> ?p ?o ?g. }

• W1559776871 endingPage "510" @default.
• W1559776871 startingPage "495" @default.
• W1559776871 abstract "Proteins and glycolipids are modified by various modes of glycosylation in the endoplasmic reticulum (ER) and the Golgi apparatus. It is well known that the lumen of the Golgi is acidic and compromising acidification by chemical compounds causes impaired glycosylation and transport of proteins (Axelsson et al., 2001, Chapman & Munro, 1994, Palokangas et al., 1994, Presley et al., 1997; Puri et al., 2002; Reaves and Banting, 1994; Rivinoja et al., 2006; Tartakoff et al., 1978). The mechanisms by which glycosylation and transport are regulated by an acidic pH remain largely unknown. Recent findings that the impaired regulation of an acidic environment may be implicated in the pathology of several diseases emphasize the importance of pH regulation (Jentsch, 2007, Kasper et al., 2005, Kornak et al., 2001, Kornak et al., 2008, Piwon et al., 2000, Stobrawa et al., 2001, Teichgraber et al., 2008). We recently established a mutant cell line in which Golgi acidification was selectively impaired and the raised luminal Golgi pH caused impaired transport and glycosylation of proteins and altered Golgi morphology (Maeda et al., 2008). As alkalinizing compounds nonselectively affect all acidic organelles including lysosomes, endosomes, and the Golgi, the mutant cell is thought to be useful in analyzing how the acidic environment of the Golgi regulates glycosylation. In this chapter, we have introduced how we established mutant cells with impaired Golgi acidification and methods for measuring Golgi pH." @default.
• W1559776871 created "2016-06-24" @default.
• W1559776871 creator A5051611788 @default.
• W1559776871 creator A5072623856 @default.
• W1559776871 date "2010-01-01" @default.
• W1559776871 modified "2023-10-15" @default.
• W1559776871 title "The Acidic Environment of the Golgi Is Critical for Glycosylation and Transport" @default.
• W1559776871 cites W1490131901 @default.
• W1559776871 cites W1494114085 @default.
• W1559776871 cites W1519402321 @default.
• W1559776871 cites W1520576380 @default.
• W1559776871 cites W1592962814 @default.
• W1559776871 cites W1885047062 @default.
• W1559776871 cites W1935776292 @default.
• W1559776871 cites W1964592202 @default.
• W1559776871 cites W1972136836 @default.
• W1559776871 cites W1979523610 @default.
• W1559776871 cites W2013702818 @default.
• W1559776871 cites W2016166286 @default.
• W1559776871 cites W2017750646 @default.
• W1559776871 cites W2020614042 @default.
• W1559776871 cites W2030035801 @default.
• W1559776871 cites W2036557000 @default.
• W1559776871 cites W2040856119 @default.
• W1559776871 cites W2041455826 @default.
• W1559776871 cites W2046585193 @default.
• W1559776871 cites W2059287499 @default.
• W1559776871 cites W2069513327 @default.
• W1559776871 cites W2074554701 @default.
• W1559776871 cites W2075761547 @default.
• W1559776871 cites W2084394815 @default.
• W1559776871 cites W2084799821 @default.
• W1559776871 cites W2086949723 @default.
• W1559776871 cites W2087552293 @default.
• W1559776871 cites W2089592662 @default.
• W1559776871 cites W2102661252 @default.
• W1559776871 cites W2103526907 @default.
• W1559776871 cites W2109662957 @default.
• W1559776871 cites W2112126161 @default.
• W1559776871 cites W2113471132 @default.
• W1559776871 cites W2114605993 @default.
• W1559776871 cites W2115710616 @default.
• W1559776871 cites W2119033790 @default.
• W1559776871 cites W2129364694 @default.
• W1559776871 cites W2137149853 @default.
• W1559776871 cites W2144692413 @default.
• W1559776871 cites W2146573893 @default.
• W1559776871 cites W2150712887 @default.
• W1559776871 cites W2151486703 @default.
• W1559776871 cites W2152155460 @default.
• W1559776871 cites W2162613182 @default.
• W1559776871 cites W2166240144 @default.
• W1559776871 cites W2172683288 @default.
• W1559776871 cites W2184457366 @default.
• W1559776871 cites W2201429489 @default.
• W1559776871 doi "https://doi.org/10.1016/s0076-6879(10)80022-9" @default.
• W1559776871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20816224" @default.
• W1559776871 hasPublicationYear "2010" @default.
• W1559776871 type Work @default.
• W1559776871 sameAs 1559776871 @default.
• W1559776871 citedByCount "29" @default.
• W1559776871 countsByYear W15597768712012 @default.
• W1559776871 countsByYear W15597768712013 @default.
• W1559776871 countsByYear W15597768712015 @default.
• W1559776871 countsByYear W15597768712016 @default.
• W1559776871 countsByYear W15597768712018 @default.
• W1559776871 countsByYear W15597768712019 @default.
• W1559776871 countsByYear W15597768712020 @default.
• W1559776871 countsByYear W15597768712021 @default.
• W1559776871 countsByYear W15597768712022 @default.
• W1559776871 countsByYear W15597768712023 @default.
• W1559776871 crossrefType "book-chapter" @default.
• W1559776871 hasAuthorship W1559776871A5051611788 @default.
• W1559776871 hasAuthorship W1559776871A5072623856 @default.
• W1559776871 hasConcept C102747710 @default.
• W1559776871 hasConcept C104317684 @default.
• W1559776871 hasConcept C119062480 @default.
• W1559776871 hasConcept C143065580 @default.
• W1559776871 hasConcept C1491633281 @default.
• W1559776871 hasConcept C158617107 @default.
• W1559776871 hasConcept C168240541 @default.
• W1559776871 hasConcept C185592680 @default.
• W1559776871 hasConcept C2777313579 @default.
• W1559776871 hasConcept C55493867 @default.
• W1559776871 hasConcept C57581600 @default.
• W1559776871 hasConcept C6492254 @default.
• W1559776871 hasConcept C86803240 @default.
• W1559776871 hasConcept C95444343 @default.
• W1559776871 hasConceptScore W1559776871C102747710 @default.
• W1559776871 hasConceptScore W1559776871C104317684 @default.
• W1559776871 hasConceptScore W1559776871C119062480 @default.
• W1559776871 hasConceptScore W1559776871C143065580 @default.
• W1559776871 hasConceptScore W1559776871C1491633281 @default.
• W1559776871 hasConceptScore W1559776871C158617107 @default.
• W1559776871 hasConceptScore W1559776871C168240541 @default.
• W1559776871 hasConceptScore W1559776871C185592680 @default.
• W1559776871 hasConceptScore W1559776871C2777313579 @default.
• W1559776871 hasConceptScore W1559776871C55493867 @default.

• next