Matches in SemOpenAlex for { <https://semopenalex.org/work/W15598596> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W15598596 endingPage "112" @default.
- W15598596 startingPage "107" @default.
- W15598596 abstract "The covalent binding of L-ascorbic acid (AA) or its degradation products to proteins (protein ascorbylation) is of importance for food chemistry and medical science. The main reaction product of mixtures of AA and alkylamines, such as propylamine or Nα-acetyllysine, was 3-deoxy-3-(alkylamino)ascorbic acid (3-DAA). When L-dehydroascorbic acid (DHA), the primary oxidation product of AA, was reacted, several products could be detected using HPLC-DAD. The four major compounds were identified as 2-deoxy-2-(alkylamino)ascorbic acid (2-DAA), 3-DAA, oxalic acid monoalkylamide (OMA) and oxalic acid dialkylamide (ODA). In the presence of arginine derivatives and oxygen, the main degradation product of AA was identified as Nδ-(4-(1,2-dihydroxy-3-propyliden)-3-imidazolin-5-on-2-y1)-L-ornithine (DPI). Since OMA was a major product when DHA was reacted with lysine derivatives, it was speculated that OMA may also be formed as an ascorbylation product of proteins. Thus, OMA-modified protein was synthesized and a polyclonal antibody was produced that was highly specific for OMA. In a competitive ELISA, ascorbylated protein inhibited antibody binding, indicating that OMA is formed as an ascorbylation product of proteins. Oxygen is necessary for the generation of OMA. The antibody did not show cross-reactivity with several proteins that had been glycosylated with other carbohydrates, including AGE-protein." @default.
- W15598596 created "2016-06-24" @default.
- W15598596 creator A5011818064 @default.
- W15598596 creator A5068682855 @default.
- W15598596 creator A5085132586 @default.
- W15598596 date "2005-01-01" @default.
- W15598596 modified "2023-09-23" @default.
- W15598596 title "The Maillard Reaction of Ascorbic Acid with Amino Acids and Proteins - Identification of Products" @default.
- W15598596 cites W1964477637 @default.
- W15598596 cites W1995817188 @default.
- W15598596 cites W2033280578 @default.
- W15598596 cites W2044411081 @default.
- W15598596 cites W2050368385 @default.
- W15598596 cites W2067490110 @default.
- W15598596 cites W2072969944 @default.
- W15598596 cites W2075819080 @default.
- W15598596 cites W2082518644 @default.
- W15598596 cites W2467783406 @default.
- W15598596 doi "https://doi.org/10.1533/9781845698447.2.107" @default.
- W15598596 hasPublicationYear "2005" @default.
- W15598596 type Work @default.
- W15598596 sameAs 15598596 @default.
- W15598596 citedByCount "3" @default.
- W15598596 countsByYear W155985962019 @default.
- W15598596 countsByYear W155985962020 @default.
- W15598596 crossrefType "book-chapter" @default.
- W15598596 hasAuthorship W15598596A5011818064 @default.
- W15598596 hasAuthorship W15598596A5068682855 @default.
- W15598596 hasAuthorship W15598596A5085132586 @default.
- W15598596 hasConcept C159654299 @default.
- W15598596 hasConcept C185592680 @default.
- W15598596 hasConcept C203014093 @default.
- W15598596 hasConcept C2776016237 @default.
- W15598596 hasConcept C2779211342 @default.
- W15598596 hasConcept C2781346138 @default.
- W15598596 hasConcept C2986274086 @default.
- W15598596 hasConcept C31903555 @default.
- W15598596 hasConcept C35378473 @default.
- W15598596 hasConcept C515207424 @default.
- W15598596 hasConcept C55493867 @default.
- W15598596 hasConcept C86803240 @default.
- W15598596 hasConcept C956191 @default.
- W15598596 hasConceptScore W15598596C159654299 @default.
- W15598596 hasConceptScore W15598596C185592680 @default.
- W15598596 hasConceptScore W15598596C203014093 @default.
- W15598596 hasConceptScore W15598596C2776016237 @default.
- W15598596 hasConceptScore W15598596C2779211342 @default.
- W15598596 hasConceptScore W15598596C2781346138 @default.
- W15598596 hasConceptScore W15598596C2986274086 @default.
- W15598596 hasConceptScore W15598596C31903555 @default.
- W15598596 hasConceptScore W15598596C35378473 @default.
- W15598596 hasConceptScore W15598596C515207424 @default.
- W15598596 hasConceptScore W15598596C55493867 @default.
- W15598596 hasConceptScore W15598596C86803240 @default.
- W15598596 hasConceptScore W15598596C956191 @default.
- W15598596 hasLocation W155985961 @default.
- W15598596 hasOpenAccess W15598596 @default.
- W15598596 hasPrimaryLocation W155985961 @default.
- W15598596 hasRelatedWork W1565512502 @default.
- W15598596 hasRelatedWork W1990393343 @default.
- W15598596 hasRelatedWork W1990511592 @default.
- W15598596 hasRelatedWork W2000895639 @default.
- W15598596 hasRelatedWork W2056413252 @default.
- W15598596 hasRelatedWork W2070072434 @default.
- W15598596 hasRelatedWork W2081940762 @default.
- W15598596 hasRelatedWork W2085857614 @default.
- W15598596 hasRelatedWork W2327175595 @default.
- W15598596 hasRelatedWork W759191165 @default.
- W15598596 isParatext "false" @default.
- W15598596 isRetracted "false" @default.
- W15598596 magId "15598596" @default.
- W15598596 workType "book-chapter" @default.