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- W1559911711 abstract "The Functions of Voltage-Dependent Potassium Channels in NeuronesPotassium channels are the one of the most important channel families for the establishment of the excitability in neurons and some other cells. These channels determine the resting membrane potential, the height and the duration of the action potential and the duration of refractory period. Potassium channels are genetically so diverse and they are voltage-dependent. There are more than 30 channels characterized on the biophysical ground. The separation and isolation of these channels were based on the differential voltage sensitivity, kinetic and pharmacological properties. Potassium channels play important roles particularly in the development of the inherited disorders (ataxia, epilepsy and heart arrhythmia) and disorders associated with the sense organs (deafness and blindness) that change the excitability of neurons.Potasyum iyon kanallari, sinir hucreleri ve diger hucrelerde goruldugu gibi uyarinin olusmasi icin en onemli membran kanallandir. Bu kanallar, dinlenim zar potansiyelini, aksiyon potansiyelinin yuksekligi ve suresi ile duyarsiz donemin (refraktory peryod) suresini belirler. Potasyum iyon kanallari, genetik olarak cok cesidi olup voltaja duyarlidir. Biyofiziksel olarak otuzdan fazla potasyum iyon kanali belirlenmistir. Bu kanallar, degisik derecede voltaja duyarli olmalari, kinetik ve farmakolojik ozelliklerinin farkliligi ile birbirlerinden ayrilirlar. Potasyum iyon kanallari, ozellikle sinir hucresinin uyarilabilirligini degistiren kalitsal hastaliklarda (ataksi, epilepsy, kalp aritmisi) ve duyu organlari ile ilgili bozukluklarda (sagirlik, korluk) onemli rol oynarlar." @default.
- W1559911711 created "2016-06-24" @default.
- W1559911711 creator A5004971079 @default.
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- W1559911711 date "2009-12-23" @default.
- W1559911711 modified "2023-10-18" @default.
- W1559911711 title "Sinir Hücrelerinin Voltaja Duyarlı Potasyum Membran Kanalları Ve Fonksiyonları" @default.
- W1559911711 doi "https://doi.org/10.5835/jecm.v19i3.241" @default.
- W1559911711 hasPublicationYear "2009" @default.
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