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- W1560037133 abstract "In response to various ethologically relevant stressors, oxytocin is released not only from neurohypophysial terminals into the blood, but also within distinct brain regions, for example the hypothalamic supraoptic and paraventricular nuclei, the septum and the amygdala in dependence on the quality and intensity of the stressor. Thus, oxytocin secretory activity may accompany the response of the hypothalamo-pituitary-adrenal (HPA) axis to a given stressor. In the present chapter, I try to summarize our efforts to reveal the physiological significance of intracerebrally released oxytocin in rats with respect to the regulation of the HPA axis under basal and stress conditions as well as with respect to behavioural stress responses. The effects of oxytocin appear to depend on the brain region studied and the state of activity of the animal (basal versus stress). In order to reveal interactions between the oxytocin system and the HPA axis, preliminary results are presented pointing towards a differential action of glucocorticoids on intracerebral and peripheral oxytocin release." @default.
- W1560037133 created "2016-06-24" @default.
- W1560037133 creator A5050770892 @default.
- W1560037133 date "2002-01-01" @default.
- W1560037133 modified "2023-10-17" @default.
- W1560037133 title "Chapter 12 Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo-pituitary-adrenal axis" @default.
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- W1560037133 doi "https://doi.org/10.1016/s0079-6123(02)39014-9" @default.
- W1560037133 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12436933" @default.
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