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• W1560431271 abstract "Alzheimer’s disease (AD) is a common form of neurodegeneration that entails a progressive breakdown of cognitive functions. Cognitive impairments commonly begin with noticeable difficulties in remembering recent events (Gold & Budson, 2008; Ally, Gold & Budson, 2009), as well as spatial disorientation (Duffy, Cushman & Kavcic, 2004) and semantic memory impairments (Milberg, McGlinchey-Berroth, Duncan & Higgins, 1999). As the disease progresses, AD also entails impairments to visual cognition, which encompasses processes that help us to understand what we see (Cronin-Golomb, 1995). The purpose of this chapter is to review recent progress towards understanding aspects of visual cognition in AD, including visual memory and visual attention, and then explore how this research can be applied to assist in the daily living of AD patients. Humans normally rely tremendously on vision for interacting with the world. Therefore, there is a profound impact on everyday activities when visual impairments develop. For example, Perry and Hodges (2000) showed that measures of visuospatial functions, semantic memory, and attention correlated significantly with measures of daily living in patients with AD, but measures of episodic and verbal short-term memory did not. Further, impairments to visual attention and memory in patients with mild-to-moderate AD lead to poor performance in complex situations like driving (Rizzo, Sparks, McEvoy, Viamonte, Kellison & Vecera, 2009) and measures of financial responsibility (Sherod, Griffith, Copeland, Belue, Krzywanski et al., 2009). Finally, certain visual abilities, like assembling an image from its parts, deteriorate as AD progresses, providing a reliable means of tracking the progress of AD in a given patient (Paxton, Peavy, Jenkins, Rice, Heindel & Salmon, 2007). Changes in everyday visual abilities can be observed very early in the disease, even in patients with mild cognitive impairment (MCI), which is thought to be a precursor to AD (Farias, Mungas, Reed, Harvey et al., 2006). Together, these studies suggest that measurable visual impairments in AD are strongly related to deterioration in everyday activities. Since the decline of visual abilities can have a very profound effect on daily living, a better understanding of AD-related changes to visual cognition, and the development of subsequent interventional strategies, promise to lead to improvements in patients’ quality of life. This chapter will place an emphasis on visual short-term memory (VSTM) in patients with AD, which has only recently been investigated. We will first describe the basic process of VSTM and then review the changes known to occur in AD. Then, we will review the interaction between visual attention and VSTM in AD patients and indicate how these two" @default.
• W1560431271 created "2016-06-24" @default.
• W1560431271 creator A5030932283 @default.
• W1560431271 creator A5068337752 @default.
• W1560431271 date "2011-09-06" @default.
• W1560431271 modified "2023-10-03" @default.
• W1560431271 title "Visual Cognition in Alzheimer’s Disease and Its Functional Implications" @default.
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