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- W1560742589 abstract "Since 1970s several studies have shown a significant prevalence of cardiovascular disease (CVD) among patients with end-stage renal disease (Linder et al., 1974). Among patients treated by hemodialysis and peritoneal dialysis, the prevalence of CVD is approximately 40%. Even after stratification by age, sex, race, and diabetes, CVD mortality in chronic kidney disease (CKD) patients is 10 to 20 times higher than in the general population (Foley et al., 1998). End-stage-renal-disease patients often have a high prevalence of cardiovascular risk factors as hypertension, diabetes and dyslipemia. Nevertheless, previous studies have shown that the high prevalence of CVD in hemodialysis patients is only partly explained by traditional risk factors (Cheung et al., 2000). Non-traditional risk factors have been emerged in the last decade. One of this non-traditional risk factor is C-reactive protein (CRP). In this chapter, it is tried to explain the results of several studies supporting an association between inflammation (measured by high levels of CRP), left-ventricular dysfunction and volume overload among patients with CKD and how volume overload, which is present at the very early stages of CKD, could be the main underlying factor contributing to the worse CV prognosis among these patients." @default.
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- W1560742589 date "2011-11-07" @default.
- W1560742589 modified "2023-10-02" @default.
- W1560742589 title "Biomarkers in Chronic Kidney Disease - The Linkage Between Inflammation, Ventricular Dysfunction and Overhydration" @default.
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- W1560742589 doi "https://doi.org/10.5772/23544" @default.
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