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- W1560758055 abstract "1. The technique of acrylamide-gel electrophoresis has been used to investigate the nature of the RNA synthesized in vivo in Escherichia coli immediately after phage T4 infection at 25°. Nucleic acid species coded for by the bacteria were generally found to be inhibited between 3 and 6 min after phage infection by processes depending on protein synthesis. 2. Two physically distinct classes of T4 messenger RNA appear to be made and their temporal separation suggests that they might correspond to the messages for pre-early and early proteins. This is borne out by hybridization-competition data which show that the time of their syntheses corresponds to the time of synthesis of the two broad temporal classes of RNA observed previously to occur early in infection. 3. Gel electrophoresis and hybridization-competition data both indicate that the synthesis of the larger RNA species made from 6 min after phage infection is dependent on protein synthesis." @default.
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- W1560758055 date "1970-05-01" @default.
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- W1560758055 title "Early in vitro and in vivo transcription of T4 DNA" @default.
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- W1560758055 doi "https://doi.org/10.1016/0005-2787(70)90665-9" @default.
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