FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1562014797> ?p ?o ?g. }

• W1562014797 endingPage "1989" @default.
• W1562014797 startingPage "1979" @default.
• W1562014797 abstract "Research Article1 June 1990free access Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein. J.M. Leong J.M. Leong Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. Search for more papers by this author R.S. Fournier R.S. Fournier Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. Search for more papers by this author R.R. Isberg R.R. Isberg Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. Search for more papers by this author J.M. Leong J.M. Leong Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. Search for more papers by this author R.S. Fournier R.S. Fournier Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. Search for more papers by this author R.R. Isberg R.R. Isberg Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. Search for more papers by this author Author Information J.M. Leong1, R.S. Fournier1 and R.R. Isberg1 1Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. The EMBO Journal (1990)9:1979-1989https://doi.org/10.1002/j.1460-2075.1990.tb08326.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The invasin protein of the pathogenic Yersinia pseudotuberculosis mediates entry of the bacterium into cultured mammalian cells by binding several beta 1 chain integrins. In this study, we identified the region of invasin responsible for cell recognition. Thirty-two monoclonal antibodies directed against invasin were isolated, and of those, six blocked cell attachment to invasin. These six antibodies recognized epitopes within the last 192 amino acids of invasin. Deletion mutants of invasin and maltose-binding protein (MBP)--invasin fusion proteins were generated and tested for cell attachment. All of the invasin derivatives that carried the carboxyl-terminal 192 amino acids retained cell binding activity. One carboxyl-terminal invasin fragment and seven MBP--invasin fusion proteins were purified. The purified derivatives that retained binding activity inhibited bacterial entry into cultured mammalian cells. These results indicated that the carboxyl-terminal 192 amino acids of invasin contains the integrin-binding domain, even though this region does not contain the tripeptide sequence Arg-Gly-Asp. Previous ArticleNext Article Volume 9Issue 61 June 1990In this issue RelatedDetailsLoading ..." @default.
• W1562014797 created "2016-06-24" @default.
• W1562014797 creator A5031816004 @default.
• W1562014797 creator A5035557493 @default.
• W1562014797 creator A5076382250 @default.
• W1562014797 date "1990-06-01" @default.
• W1562014797 modified "2023-10-16" @default.
• W1562014797 title "Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein." @default.
• W1562014797 cites W102410372 @default.
• W1562014797 cites W1141074930 @default.
• W1562014797 cites W120336564 @default.
• W1562014797 cites W1481884569 @default.
• W1562014797 cites W1590204800 @default.
• W1562014797 cites W1601687245 @default.
• W1562014797 cites W1755737437 @default.
• W1562014797 cites W1775749144 @default.
• W1562014797 cites W1844896946 @default.
• W1562014797 cites W1883019490 @default.
• W1562014797 cites W1892644136 @default.
• W1562014797 cites W1903506151 @default.
• W1562014797 cites W1917680451 @default.
• W1562014797 cites W1921037547 @default.
• W1562014797 cites W1952304498 @default.
• W1562014797 cites W1966485125 @default.
• W1562014797 cites W1968209610 @default.
• W1562014797 cites W1969540615 @default.
• W1562014797 cites W1973125631 @default.
• W1562014797 cites W1980640496 @default.
• W1562014797 cites W1987568997 @default.
• W1562014797 cites W1987580186 @default.
• W1562014797 cites W1990387345 @default.
• W1562014797 cites W2005165360 @default.
• W1562014797 cites W2005579644 @default.
• W1562014797 cites W2006271637 @default.
• W1562014797 cites W2008132225 @default.
• W1562014797 cites W2012604733 @default.
• W1562014797 cites W2013381560 @default.
• W1562014797 cites W2016545287 @default.
• W1562014797 cites W2018289835 @default.
• W1562014797 cites W2020690016 @default.
• W1562014797 cites W2028622989 @default.
• W1562014797 cites W2029766804 @default.
• W1562014797 cites W2032462421 @default.
• W1562014797 cites W2039241460 @default.
• W1562014797 cites W2041534105 @default.
• W1562014797 cites W2043248449 @default.
• W1562014797 cites W2044801740 @default.
• W1562014797 cites W2062582674 @default.
• W1562014797 cites W2064484362 @default.
• W1562014797 cites W2068518785 @default.
• W1562014797 cites W2074116762 @default.
• W1562014797 cites W2093431241 @default.
• W1562014797 cites W2094507656 @default.
• W1562014797 cites W2100837269 @default.
• W1562014797 cites W2101108802 @default.
• W1562014797 cites W2104685950 @default.
• W1562014797 cites W2105300288 @default.
• W1562014797 cites W2109062164 @default.
• W1562014797 cites W2125832990 @default.
• W1562014797 cites W2128647672 @default.
• W1562014797 cites W2138401175 @default.
• W1562014797 cites W2138539863 @default.
• W1562014797 cites W2169318446 @default.
• W1562014797 cites W2293579233 @default.
• W1562014797 cites W2327377968 @default.
• W1562014797 cites W2414674927 @default.
• W1562014797 cites W2474452953 @default.
• W1562014797 cites W931222270 @default.
• W1562014797 cites W998175253 @default.
• W1562014797 cites W4290297005 @default.
• W1562014797 doi "https://doi.org/10.1002/j.1460-2075.1990.tb08326.x" @default.
• W1562014797 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/551907" @default.
• W1562014797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1693333" @default.
• W1562014797 hasPublicationYear "1990" @default.
• W1562014797 type Work @default.
• W1562014797 sameAs 1562014797 @default.
• W1562014797 citedByCount "230" @default.
• W1562014797 countsByYear W15620147972012 @default.
• W1562014797 countsByYear W15620147972013 @default.
• W1562014797 countsByYear W15620147972014 @default.
• W1562014797 countsByYear W15620147972015 @default.
• W1562014797 countsByYear W15620147972016 @default.
• W1562014797 countsByYear W15620147972018 @default.
• W1562014797 countsByYear W15620147972019 @default.
• W1562014797 countsByYear W15620147972020 @default.
• W1562014797 countsByYear W15620147972021 @default.
• W1562014797 countsByYear W15620147972022 @default.
• W1562014797 countsByYear W15620147972023 @default.
• W1562014797 crossrefType "journal-article" @default.
• W1562014797 hasAuthorship W1562014797A5031816004 @default.
• W1562014797 hasAuthorship W1562014797A5035557493 @default.
• W1562014797 hasAuthorship W1562014797A5076382250 @default.
• W1562014797 hasBestOaLocation W15620147971 @default.
• W1562014797 hasConcept C104317684 @default.
• W1562014797 hasConcept C161191863 @default.
• W1562014797 hasConcept C2776255393 @default.
• W1562014797 hasConcept C2777353990 @default.
• W1562014797 hasConcept C2992965680 @default.

• next