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- W156235311 abstract "Modern cancer therapeutic research is at crossroads in evolving our approaches to discovering, developing, and entering novel therapeutics into early-stage clinical trials. This chapter endeavors to summarize the customary use and interpretation of animal models used for prioritization of cancer treatments for entry into clinical trials through the end of the last century. We then consider the novel screening paradigms currently in use which exemplify the diverse types of challenging lead compounds for in vivo evaluation. Finally, we offer a strategic overview of steps to maximize utility of the animal model information in selecting agents for clinical study in the twenty-first century." @default.
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- W156235311 date "2010-11-20" @default.
- W156235311 modified "2023-10-14" @default.
- W156235311 title "Perspectives on the History and Evolution of Tumor Models" @default.
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- W156235311 doi "https://doi.org/10.1007/978-1-60761-968-0_1" @default.
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