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- W156236710 endingPage "239e" @default.
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- W156236710 abstract "Therapeutic embolisation of blood vessels is a procedure commonly performed to treat a variety of conditions including bleeding problems, arterio-venous malformations (AVM), and benign and malignant hypervascular tumours. A range of degradable and permanent embolisation devices composed of natural and synthetic polymers may be used for such applications. Beads composed of a sulfonate-modified poly(vinyl alcohol) (PVA) hydrogel (DC Bead®) are finding wide-spread use for the occlusion and subsequent local, controlled and sustained delivery of chemotherapeutic agents directly within the vasculature of liver tumours. These so-called drug-eluting beads (DEB) are available in a series of calibrated size ranges for matching vessel size; have appropriate physico-mechanical properties to enable them to be delivered with ease through narrow gauge microcatheters; and have the ability to actively sequester and release positively charged anticancer drugs by an ion-exchange mechanism. This product has become one of the standards of care in the Western World for the treatment of intermediate primary liver cancer." @default.
- W156236710 created "2016-06-24" @default.
- W156236710 creator A5022763205 @default.
- W156236710 date "2013-01-01" @default.
- W156236710 modified "2023-09-23" @default.
- W156236710 title "Embolisation devices from biomedical polymers for intra-arterial occlusion and drug delivery in the treatment of cancer" @default.
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- W156236710 doi "https://doi.org/10.1533/9780857096760.3.207" @default.
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