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- W1562508739 abstract "Although monoamine oxidase (MAO) inhibitors are not used as extensively as other antidepressants, they continue to have an important place in the armamentarium of drugs used to treat psychiatric and neurological disorders. Interest in MAO inhibitors has also increased in recent years because of numerous reports of their neuroprotective/neurorescue properties.1–5 Such studies have resulted in a better understanding of possible mechanisms of neuroprotection; stimulated the development of new drugs, such as rasagiline; provided important clues for the development of other drugs for neuropsychiatric disorders; and contributed to the recent surge of interest in possible neuroprotective actions of psychiatric drugs in general.6,7 Intriguingly, they have also demonstrated that the MAO inhibitors currently available are multifaceted, since, in many cases, the neuroprotection seems to be independent of their MAO inhibition. Studies on semicarbazide-sensitive amine oxidase (SSAO) and its inhibition have also provided exciting results that are relevant to neuropsychiatric disorders and associated diabetes and cardiovascular disease.8,9 These findings are outlined briefly below." @default.
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- W1562508739 date "2007-09-01" @default.
- W1562508739 modified "2023-09-27" @default.
- W1562508739 title "Amine oxidases and their inhibitors: what can they tell us about neuroprotection and the development of drugs for neuropsychiatric disorders?" @default.
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- W1562508739 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1963356" @default.
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