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- W1562542164 abstract "Low density lipoprotein (LDL-C) levels determine the cardiovascular risk. Previous studies indicated an LDL-C target attainment of around 50 %, but no Austrian wide analysis on results for the federal states was available. We therefore sought to detect potential differences. Design: Open-label, non-interventional, longitudinal study, registered: www.clinicaltrials.gov NCT 01381679. In all, 746 statin treated patients not at LDL-C goal received intensified therapy for 12 months. The sample was split into nine subgroups, representing the federal states of Austria. We detected an east-west gradient for baseline LDL-C. Individual target values were achieved by 37.2 % (range: 26.1–57.7 %). After 12 months, LDL-C < 70 mg/l was achieved by 13.5 % (5.9–38.5 %). Univariate ANCOVA retrieved significant differences within the states (Upper Austria and Salzburg, p = 0.001 and p = 0.0015, respectively). Furthermore, the capacity of intensified lipid lowering therapy applied in practice was as high as −42 % as compared to previous standard therapy (additional LDL-C reduction after switch from baseline therapy in Vorarlberg)." @default.
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- W1562542164 date "2013-08-27" @default.
- W1562542164 modified "2023-10-01" @default.
- W1562542164 title "Are there differences in LDL-C target value attainment in Austrian federal states? Yes!" @default.
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- W1562542164 doi "https://doi.org/10.1007/s10354-013-0219-z" @default.
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