FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1562814494> ?p ?o ?g. }

• W1562814494 endingPage "958" @default.
• W1562814494 startingPage "953" @default.
• W1562814494 abstract "To elucidate the effect of testosterone on penile innervation. Materials and methods Three groups of six rats each were assessed; two groups (1 and 2) were castrated and the third (group 3) underwent a sham operation (control). Eight weeks after castration, group 2 received a subcutaneous injection with testosterone. At 8 weeks, the rats in group 1 and 3 underwent a final functional analysis while those in group 2 did so at 12 weeks. The evaluation included a subcutaneous injection with apomorphine to study centrally mediated erection, and cavernosal nerve electrostimulation and papaverine injection to study peripherally mediated erection. At death a penile mid-shaft specimen was taken for NADPH-diaphorase staining.In the apomorphine study, castration resulted in significantly fewer yawns and erections than in the control, and those in group 2 significantly better central erectile function than in the controls. The mean (SEM) number of nitric oxide synthase (NOS)-containing nerve fibres in the corpora cavernosa and both dorsal nerves of castrated rats, at 46.2 (9.1) and 203 (32.1), respectively, were significantly lower than in rats in group 2, at 84.1 (11.2) and 300.6 (17.1), and than in the controls, at 88.6 (10.9) and 306.3 (22.9), respectively. The intracavernosal pressure decreased significantly in the absence of testosterone, both after electrostimulation and intracavernosal papaverine injection. However, there was no difference between the control and group 2 rats in either the number of NOS-containing nerve fibres or in the peripheral erectile functional study.Testosterone acts on the nervous system to mediate erection; when it is absent there may be down-regulation of both the production and activity of NO, thereby decreasing the response to peripheral stimulation via the NO pathway. The restoration of erectile function seen in rats in group 2 supports this phenomenon. Delayed testosterone replacement has no detrimental effect on the restoration of the erectile mechanism after castration." @default.
• W1562814494 created "2016-06-24" @default.
• W1562814494 creator A5026898197 @default.
• W1562814494 creator A5031134013 @default.
• W1562814494 creator A5042849164 @default.
• W1562814494 creator A5049331920 @default.
• W1562814494 creator A5057327430 @default.
• W1562814494 creator A5073838776 @default.
• W1562814494 creator A5081192418 @default.
• W1562814494 date "2001-12-24" @default.
• W1562814494 modified "2023-10-18" @default.
• W1562814494 title "Delayed testosterone replacement restores nitric oxide synthase-containing nerve fibres and the erectile response in rat penis" @default.
• W1562814494 cites W120498402 @default.
• W1562814494 cites W1966322594 @default.
• W1562814494 cites W1968395684 @default.
• W1562814494 cites W1968594713 @default.
• W1562814494 cites W1969777930 @default.
• W1562814494 cites W1971268704 @default.
• W1562814494 cites W1976565117 @default.
• W1562814494 cites W1979474986 @default.
• W1562814494 cites W1979521526 @default.
• W1562814494 cites W2003550690 @default.
• W1562814494 cites W2008782209 @default.
• W1562814494 cites W2011297952 @default.
• W1562814494 cites W2019613587 @default.
• W1562814494 cites W2025785329 @default.
• W1562814494 cites W2028971791 @default.
• W1562814494 cites W2030309210 @default.
• W1562814494 cites W2031819036 @default.
• W1562814494 cites W2035464530 @default.
• W1562814494 cites W2045797639 @default.
• W1562814494 cites W2048369893 @default.
• W1562814494 cites W2066949311 @default.
• W1562814494 cites W2068747635 @default.
• W1562814494 cites W2297865121 @default.
• W1562814494 cites W2402399220 @default.
• W1562814494 cites W8319256 @default.
• W1562814494 cites W2001922338 @default.
• W1562814494 doi "https://doi.org/10.1046/j.1464-410x.2000.00598.x" @default.
• W1562814494 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10792181" @default.
• W1562814494 hasPublicationYear "2001" @default.
• W1562814494 type Work @default.
• W1562814494 sameAs 1562814494 @default.
• W1562814494 citedByCount "100" @default.
• W1562814494 countsByYear W15628144942012 @default.
• W1562814494 countsByYear W15628144942013 @default.
• W1562814494 countsByYear W15628144942014 @default.
• W1562814494 countsByYear W15628144942015 @default.
• W1562814494 countsByYear W15628144942016 @default.
• W1562814494 countsByYear W15628144942017 @default.
• W1562814494 countsByYear W15628144942018 @default.
• W1562814494 countsByYear W15628144942019 @default.
• W1562814494 countsByYear W15628144942020 @default.
• W1562814494 countsByYear W15628144942021 @default.
• W1562814494 countsByYear W15628144942022 @default.
• W1562814494 countsByYear W15628144942023 @default.
• W1562814494 crossrefType "journal-article" @default.
• W1562814494 hasAuthorship W1562814494A5026898197 @default.
• W1562814494 hasAuthorship W1562814494A5031134013 @default.
• W1562814494 hasAuthorship W1562814494A5042849164 @default.
• W1562814494 hasAuthorship W1562814494A5049331920 @default.
• W1562814494 hasAuthorship W1562814494A5057327430 @default.
• W1562814494 hasAuthorship W1562814494A5073838776 @default.
• W1562814494 hasAuthorship W1562814494A5081192418 @default.
• W1562814494 hasConcept C126322002 @default.
• W1562814494 hasConcept C126894567 @default.
• W1562814494 hasConcept C134018914 @default.
• W1562814494 hasConcept C137183658 @default.
• W1562814494 hasConcept C141071460 @default.
• W1562814494 hasConcept C2776390293 @default.
• W1562814494 hasConcept C2776952824 @default.
• W1562814494 hasConcept C2777525119 @default.
• W1562814494 hasConcept C2777622882 @default.
• W1562814494 hasConcept C2777786686 @default.
• W1562814494 hasConcept C2778509035 @default.
• W1562814494 hasConcept C2779256933 @default.
• W1562814494 hasConcept C2779279991 @default.
• W1562814494 hasConcept C2779929075 @default.
• W1562814494 hasConcept C42219234 @default.
• W1562814494 hasConcept C513476851 @default.
• W1562814494 hasConcept C519581460 @default.
• W1562814494 hasConcept C71315377 @default.
• W1562814494 hasConcept C71924100 @default.
• W1562814494 hasConceptScore W1562814494C126322002 @default.
• W1562814494 hasConceptScore W1562814494C126894567 @default.
• W1562814494 hasConceptScore W1562814494C134018914 @default.
• W1562814494 hasConceptScore W1562814494C137183658 @default.
• W1562814494 hasConceptScore W1562814494C141071460 @default.
• W1562814494 hasConceptScore W1562814494C2776390293 @default.
• W1562814494 hasConceptScore W1562814494C2776952824 @default.
• W1562814494 hasConceptScore W1562814494C2777525119 @default.
• W1562814494 hasConceptScore W1562814494C2777622882 @default.
• W1562814494 hasConceptScore W1562814494C2777786686 @default.
• W1562814494 hasConceptScore W1562814494C2778509035 @default.
• W1562814494 hasConceptScore W1562814494C2779256933 @default.
• W1562814494 hasConceptScore W1562814494C2779279991 @default.
• W1562814494 hasConceptScore W1562814494C2779929075 @default.
• W1562814494 hasConceptScore W1562814494C42219234 @default.

• next