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- W1563064498 abstract "Publisher Summary The chapter discusses pseudodistomins, their occurrence, structure, synthesis, and pharmacology. The first paper regarding the series of natural products appeared in 1987 on the isolation and structure proposal of pseudodistomins A and B. The structures of pseudodistomins A and B were proposed based mainly on the assignment of their 1 H and 13 C NMR spectra. Pseudodistomins A and B were readily hydrogenated at the dienyl group in their side chains to afford an identical tetrahydro-pseudodistomin, which played a key role in their initial structure determination. Four syntheses of this structure have been reported, almost at the same time, in 1992–1994. Natsume e t al. had developed a new type of carbon–carbon bond forming reaction using singlet oxygen and succeeded in applying this reaction to hydropyridines and then to tetrahydro-pseudodistomin. Pharmacological results were reported on the components from the other tunicates, such as Pseudodistoma cruciparta , Pseudodistoma novaezelandiae, and Pseudodistoma crucigaster ." @default.
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- W1563064498 date "1998-01-01" @default.
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- W1563064498 title "Chapter 8 Pseudodistomins: Structure, Synthesis, and Pharmacology" @default.
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- W1563064498 doi "https://doi.org/10.1016/s1099-4831(08)60046-2" @default.
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