FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1563173655> ?p ?o ?g. }

• W1563173655 endingPage "1810" @default.
• W1563173655 startingPage "1805" @default.
• W1563173655 abstract "Adipose tissue has been reported to contain relatively high levels of the specific mRNA for retinol-binding protein (RBP) (Makover A., Soprano, D.R., Wyatt, M. L., and Goodman, D.S. (1989) J. Lipid Res. 30, 171-180). Studies were conducted to explore retinoid and retinoid-binding protein storage and metabolism in adipose tissue. In these studies, we measured RBP and cellular retinol-binding protein (CRBP) mRNA levels and retinoid levels in 6 adipose depots in male rats. Total RNA was isolated from inguinal, dorsal, mesenteric, epididymal, perinephric, and brown adipose tissue, and average RBP and CRBP mRNA levels were determined by Northern blot analysis. The relative levels of RBP mRNA in these 6 anatomically different adipose depots averaged, respectively, 6.3, 6.7, 16, 34, 37, and 21% of the level in a rat liver RNA standard. Retinoid levels in the 6 depots were similar and averaged approximately 6-7 micrograms of retinol eq/g of adipose tissue. Since adipose tissue contains several cell types, the cellular localizations of RBP and CRBP expression and retinoid storage were examined. RNA was prepared from isolated rat adipocytes and stromal-vascular cells. Cellular levels of the mRNAs for RBP, CRBP, apolipoprotein E (apoE), lipoprotein lipase, adipocyte P2, and adipsin were measured by Northern blot analysis. RBP was expressed almost exclusively in the adipocytes and only weakly in the stromal-vascular cells. Both CRBP and apoE mRNA levels were relatively high in the stromal-vascular cell preparations and only very low mRNA levels were found in the adipocytes. Lipoprotein lipase, adipsin, and adipocyte P2 mRNAs were found in substantial levels in both the adipocytes and stromal-vascular cells, but with higher levels present in the adipocytes. Cultured adipocytes synthesized RBP protein and secreted it into the medium. Only adipocytes (not stromal-vascular cells) contained retinol, at levels between 0.65-0.8 micrograms of retinol eq/10(6) cells. These studies demonstrate that adipocytes store retinoid and synthesize and secrete RBP, and suggest that rat adipocytes may be dynamically involved in retinoid storage and metabolism." @default.
• W1563173655 created "2016-06-24" @default.
• W1563173655 creator A5018829254 @default.
• W1563173655 creator A5032881650 @default.
• W1563173655 creator A5038273896 @default.
• W1563173655 creator A5046613446 @default.
• W1563173655 creator A5048119786 @default.
• W1563173655 creator A5069241630 @default.
• W1563173655 creator A5069587223 @default.
• W1563173655 date "1992-01-01" @default.
• W1563173655 modified "2023-10-01" @default.
• W1563173655 title "Retinoids and retinoid-binding protein expression in rat adipocytes." @default.
• W1563173655 cites W1493030029 @default.
• W1563173655 cites W1535908151 @default.
• W1563173655 cites W1560052983 @default.
• W1563173655 cites W1568773554 @default.
• W1563173655 cites W1591157154 @default.
• W1563173655 cites W1870501054 @default.
• W1563173655 cites W1911364508 @default.
• W1563173655 cites W1926274025 @default.
• W1563173655 cites W1971889217 @default.
• W1563173655 cites W1984753323 @default.
• W1563173655 cites W2005773979 @default.
• W1563173655 cites W2009316714 @default.
• W1563173655 cites W2011418719 @default.
• W1563173655 cites W2023466759 @default.
• W1563173655 cites W2030488757 @default.
• W1563173655 cites W2037774298 @default.
• W1563173655 cites W2044808887 @default.
• W1563173655 cites W2048613378 @default.
• W1563173655 cites W2048978769 @default.
• W1563173655 cites W2049791242 @default.
• W1563173655 cites W2052506884 @default.
• W1563173655 cites W2069710660 @default.
• W1563173655 cites W2072233737 @default.
• W1563173655 cites W2083436346 @default.
• W1563173655 cites W2085284028 @default.
• W1563173655 cites W2100837269 @default.
• W1563173655 cites W2125636545 @default.
• W1563173655 cites W2136386244 @default.
• W1563173655 cites W2143873575 @default.
• W1563173655 cites W2161499059 @default.
• W1563173655 cites W2167033537 @default.
• W1563173655 cites W2167877064 @default.
• W1563173655 cites W2168526937 @default.
• W1563173655 cites W2185523019 @default.
• W1563173655 cites W2286101656 @default.
• W1563173655 cites W2327310966 @default.
• W1563173655 cites W2409611136 @default.
• W1563173655 cites W343065178 @default.
• W1563173655 cites W4294216491 @default.
• W1563173655 cites W999372762 @default.
• W1563173655 doi "https://doi.org/10.1016/s0021-9258(18)46017-6" @default.
• W1563173655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1370481" @default.
• W1563173655 hasPublicationYear "1992" @default.
• W1563173655 type Work @default.
• W1563173655 sameAs 1563173655 @default.
• W1563173655 citedByCount "274" @default.
• W1563173655 countsByYear W15631736552012 @default.
• W1563173655 countsByYear W15631736552013 @default.
• W1563173655 countsByYear W15631736552014 @default.
• W1563173655 countsByYear W15631736552015 @default.
• W1563173655 countsByYear W15631736552016 @default.
• W1563173655 countsByYear W15631736552017 @default.
• W1563173655 countsByYear W15631736552018 @default.
• W1563173655 countsByYear W15631736552019 @default.
• W1563173655 countsByYear W15631736552020 @default.
• W1563173655 countsByYear W15631736552021 @default.
• W1563173655 countsByYear W15631736552022 @default.
• W1563173655 countsByYear W15631736552023 @default.
• W1563173655 crossrefType "journal-article" @default.
• W1563173655 hasAuthorship W1563173655A5018829254 @default.
• W1563173655 hasAuthorship W1563173655A5032881650 @default.
• W1563173655 hasAuthorship W1563173655A5038273896 @default.
• W1563173655 hasAuthorship W1563173655A5046613446 @default.
• W1563173655 hasAuthorship W1563173655A5048119786 @default.
• W1563173655 hasAuthorship W1563173655A5069241630 @default.
• W1563173655 hasAuthorship W1563173655A5069587223 @default.
• W1563173655 hasBestOaLocation W15631736551 @default.
• W1563173655 hasConcept C104317684 @default.
• W1563173655 hasConcept C126322002 @default.
• W1563173655 hasConcept C134018914 @default.
• W1563173655 hasConcept C185592680 @default.
• W1563173655 hasConcept C2775954498 @default.
• W1563173655 hasConcept C2781121885 @default.
• W1563173655 hasConcept C51639874 @default.
• W1563173655 hasConcept C55493867 @default.
• W1563173655 hasConcept C6856738 @default.
• W1563173655 hasConcept C71924100 @default.
• W1563173655 hasConcept C86803240 @default.
• W1563173655 hasConcept C95444343 @default.
• W1563173655 hasConceptScore W1563173655C104317684 @default.
• W1563173655 hasConceptScore W1563173655C126322002 @default.
• W1563173655 hasConceptScore W1563173655C134018914 @default.
• W1563173655 hasConceptScore W1563173655C185592680 @default.
• W1563173655 hasConceptScore W1563173655C2775954498 @default.
• W1563173655 hasConceptScore W1563173655C2781121885 @default.
• W1563173655 hasConceptScore W1563173655C51639874 @default.

• next