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- W1564614588 abstract "Mast cells appear to play significant roles in physiological and pathological conditions. Some functions of mast cells may relate to liver cirrhosis, which is characterized by degeneration, necrosis and regeneration of parenchyma as well as fibrosis, but little information regarding this association has been obtained. This study was carried (Jut in order to clarify the pathogenesis of liver cirrhosis as related to the distribution and the role of mast cells. Fifty-five cases of liver cirrhosis were divided into five groups, according to Kim's morphological classi fication and the mean values with the standard errors in each group were deter mined with regard to the number of mast cells, the relative volume of the trabe cula and the liver weight. A statistical analysis of these determinations was also performed. The results of the present investigation revealed that a greater number of mast cells were found in the I-B and the n-B groups in which a more marked regeneration was histopathologically recognized, and that in these groups a statistically significant correlation existed between the number of mast cells and the liver weight which mostly increased with regeneration. These findings strongly suggested that mast cells in human liver cirrhosis had a close relation ship to regeneration of hepatic parenchyma followed by occasional incidence of malignant hepatomas." @default.
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- W1564614588 date "1971-09-01" @default.
- W1564614588 modified "2023-09-23" @default.
- W1564614588 title "The role of mast cells in human liver cirrhosis." @default.
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