FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1564877589> ?p ?o ?g. }

• W1564877589 endingPage "2393" @default.
• W1564877589 startingPage "2390" @default.
• W1564877589 abstract "Cell-free translations of ovine pituitary RNA were used to examine the amount of alpha subunit synthesized in the presence and absence of physiological levels of gonadal steroids. Two animal groups were used: 1) no feedback-castrate ewes exhibiting high serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and 2) negative feedback-castrate ewes treated with estradiol and progesterone which suppressed LH and FSH secretion. Cytoplasmic RNA was extracted from the pituitaries, translated in a wheat germ cell-free system, and alpha subunit identified by specific immunoprecipitation and sodium dodecyl sulfate-polyacrylamide gels. Low amounts of alpha subunit (0.06% of total incorporated trichloroacetic acid-insoluble cpm) were seen in steroid-treated castrate ewes which also exhibited low serum LH and FSH concentrations. The amount of alpha translated by pituitary RNA from untreated castrates was significantly higher than those amounts from the steroid-treated castrates (p less than 0.02). The decreased amount of translated alpha subunit in steroid-treated castrates was probably not due to unique in vitro translation properties since the isotope incorporated/microgram of RNA and the amount of translated growth hormone and prolactin were similar for all RNAs. The results obtained from this animal model system suggest that the chronic negative feedback action of gonadal steroids on the gonadotropic hormones is effected, in part, via inhibition of synthesis of the alpha subunit of LH and FSH." @default.
• W1564877589 created "2016-06-24" @default.
• W1564877589 creator A5026207971 @default.
• W1564877589 creator A5033192336 @default.
• W1564877589 creator A5038390973 @default.
• W1564877589 date "1983-02-01" @default.
• W1564877589 modified "2023-09-28" @default.
• W1564877589 title "Regulation of alpha subunit synthesis by gonadal steroid feedback in the sheep anterior pituitary." @default.
• W1564877589 cites W147138264 @default.
• W1564877589 cites W1532528754 @default.
• W1564877589 cites W1559030713 @default.
• W1564877589 cites W1562512611 @default.
• W1564877589 cites W1591714527 @default.
• W1564877589 cites W1602608751 @default.
• W1564877589 cites W1608716905 @default.
• W1564877589 cites W168504699 @default.
• W1564877589 cites W1861067686 @default.
• W1564877589 cites W1971563036 @default.
• W1564877589 cites W1978555945 @default.
• W1564877589 cites W1992121800 @default.
• W1564877589 cites W2008965371 @default.
• W1564877589 cites W2015555892 @default.
• W1564877589 cites W2026592554 @default.
• W1564877589 cites W2028484496 @default.
• W1564877589 cites W2069072616 @default.
• W1564877589 cites W2082161003 @default.
• W1564877589 cites W2083424490 @default.
• W1564877589 cites W2092380159 @default.
• W1564877589 cites W2110790549 @default.
• W1564877589 cites W2111703289 @default.
• W1564877589 cites W2130370488 @default.
• W1564877589 cites W2140388857 @default.
• W1564877589 cites W2141378716 @default.
• W1564877589 cites W2142400691 @default.
• W1564877589 cites W2155948328 @default.
• W1564877589 doi "https://doi.org/10.1016/s0021-9258(18)32936-3" @default.
• W1564877589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6185495" @default.
• W1564877589 hasPublicationYear "1983" @default.
• W1564877589 type Work @default.
• W1564877589 sameAs 1564877589 @default.
• W1564877589 citedByCount "30" @default.
• W1564877589 crossrefType "journal-article" @default.
• W1564877589 hasAuthorship W1564877589A5026207971 @default.
• W1564877589 hasAuthorship W1564877589A5033192336 @default.
• W1564877589 hasAuthorship W1564877589A5038390973 @default.
• W1564877589 hasBestOaLocation W15648775891 @default.
• W1564877589 hasConcept C104292427 @default.
• W1564877589 hasConcept C104317684 @default.
• W1564877589 hasConcept C126322002 @default.
• W1564877589 hasConcept C134018914 @default.
• W1564877589 hasConcept C159110408 @default.
• W1564877589 hasConcept C185592680 @default.
• W1564877589 hasConcept C197012351 @default.
• W1564877589 hasConcept C2775944032 @default.
• W1564877589 hasConcept C2776888042 @default.
• W1564877589 hasConcept C2778575703 @default.
• W1564877589 hasConcept C2779029589 @default.
• W1564877589 hasConcept C2779064019 @default.
• W1564877589 hasConcept C2779279165 @default.
• W1564877589 hasConcept C2780902042 @default.
• W1564877589 hasConcept C49453240 @default.
• W1564877589 hasConcept C55493867 @default.
• W1564877589 hasConcept C64943373 @default.
• W1564877589 hasConcept C67705224 @default.
• W1564877589 hasConcept C71315377 @default.
• W1564877589 hasConcept C71924100 @default.
• W1564877589 hasConcept C83730767 @default.
• W1564877589 hasConcept C86803240 @default.
• W1564877589 hasConceptScore W1564877589C104292427 @default.
• W1564877589 hasConceptScore W1564877589C104317684 @default.
• W1564877589 hasConceptScore W1564877589C126322002 @default.
• W1564877589 hasConceptScore W1564877589C134018914 @default.
• W1564877589 hasConceptScore W1564877589C159110408 @default.
• W1564877589 hasConceptScore W1564877589C185592680 @default.
• W1564877589 hasConceptScore W1564877589C197012351 @default.
• W1564877589 hasConceptScore W1564877589C2775944032 @default.
• W1564877589 hasConceptScore W1564877589C2776888042 @default.
• W1564877589 hasConceptScore W1564877589C2778575703 @default.
• W1564877589 hasConceptScore W1564877589C2779029589 @default.
• W1564877589 hasConceptScore W1564877589C2779064019 @default.
• W1564877589 hasConceptScore W1564877589C2779279165 @default.
• W1564877589 hasConceptScore W1564877589C2780902042 @default.
• W1564877589 hasConceptScore W1564877589C49453240 @default.
• W1564877589 hasConceptScore W1564877589C55493867 @default.
• W1564877589 hasConceptScore W1564877589C64943373 @default.
• W1564877589 hasConceptScore W1564877589C67705224 @default.
• W1564877589 hasConceptScore W1564877589C71315377 @default.
• W1564877589 hasConceptScore W1564877589C71924100 @default.
• W1564877589 hasConceptScore W1564877589C83730767 @default.
• W1564877589 hasConceptScore W1564877589C86803240 @default.
• W1564877589 hasIssue "4" @default.
• W1564877589 hasLocation W15648775891 @default.
• W1564877589 hasOpenAccess W1564877589 @default.
• W1564877589 hasPrimaryLocation W15648775891 @default.
• W1564877589 hasRelatedWork W147138264 @default.
• W1564877589 hasRelatedWork W147713268 @default.
• W1564877589 hasRelatedWork W1532528754 @default.
• W1564877589 hasRelatedWork W1537080078 @default.

• next