Matches in SemOpenAlex for { <https://semopenalex.org/work/W1565149579> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1565149579 endingPage "32" @default.
- W1565149579 startingPage "27" @default.
- W1565149579 abstract "Recently there has been considerable original research into the use of the botulinum neurotoxins in idiopathic detrusor overactivity (DO). This common condition underlies the overactive bladder syndrome in a significant proportion of cases and was previously known as idiopathic detrusor instability. Failure of initial pharmacotherapy in this condition leaves few effective conservative/medical treatment options. Early reports of botulinum toxin (BoNT) therapy have been extremely promising, and the therapy appears to bridge the gap in such patients, before resorting to invasive surgical procedures. Approximately 30 studies have been reported often with widely differing techniques and some clinicians are beginning to administer BoNT for this unlicensed indication. This has led to the urgent need to critically review all available evidence to assess efficacy, safety and technique. In addition to performing a systematic Medline review, all abstracts presented to urological, urogynaecological and incontinence meetings that reported BoNT usage in idiopathic DO were analysed. Remarkable efficacy has been demonstrated in the vast majority of reported series and the treatment has also been used safely in paediatric and elderly populations. Side effects in all populations appear to be minimal and short lived. However, all the series are small and there remains a considerable number of fundamental questions to be answered. Hopefully large-scale robust randomised controlled trials will provide the necessary answers to facilitate the widespread adoption of this technique. Until then caution must be exercised in this unlicensed indication." @default.
- W1565149579 created "2016-06-24" @default.
- W1565149579 creator A5049686705 @default.
- W1565149579 creator A5079097918 @default.
- W1565149579 creator A5080266362 @default.
- W1565149579 date "2006-11-22" @default.
- W1565149579 modified "2023-09-27" @default.
- W1565149579 title "The emerging role of intravesical botulinum toxin therapy in idiopathic detrusor overactivity" @default.
- W1565149579 cites W1257881779 @default.
- W1565149579 cites W1965002957 @default.
- W1565149579 cites W1967312126 @default.
- W1565149579 cites W1969297831 @default.
- W1565149579 cites W1976363592 @default.
- W1565149579 cites W1977141080 @default.
- W1565149579 cites W1983196590 @default.
- W1565149579 cites W1989319717 @default.
- W1565149579 cites W1995640447 @default.
- W1565149579 cites W1998995174 @default.
- W1565149579 cites W1999752640 @default.
- W1565149579 cites W2000821561 @default.
- W1565149579 cites W2007875052 @default.
- W1565149579 cites W2017235586 @default.
- W1565149579 cites W2051448097 @default.
- W1565149579 cites W2057855540 @default.
- W1565149579 cites W2061739521 @default.
- W1565149579 cites W2062168648 @default.
- W1565149579 cites W2063307429 @default.
- W1565149579 cites W2079262318 @default.
- W1565149579 cites W2087510752 @default.
- W1565149579 cites W2087742865 @default.
- W1565149579 cites W2107593389 @default.
- W1565149579 cites W2126110442 @default.
- W1565149579 cites W2134928141 @default.
- W1565149579 cites W2149217550 @default.
- W1565149579 cites W2792477482 @default.
- W1565149579 doi "https://doi.org/10.1111/j.1742-1241.2006.01212.x" @default.
- W1565149579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17169008" @default.
- W1565149579 hasPublicationYear "2006" @default.
- W1565149579 type Work @default.
- W1565149579 sameAs 1565149579 @default.
- W1565149579 citedByCount "6" @default.
- W1565149579 countsByYear W15651495792013 @default.
- W1565149579 countsByYear W15651495792014 @default.
- W1565149579 countsByYear W15651495792015 @default.
- W1565149579 crossrefType "journal-article" @default.
- W1565149579 hasAuthorship W1565149579A5049686705 @default.
- W1565149579 hasAuthorship W1565149579A5079097918 @default.
- W1565149579 hasAuthorship W1565149579A5080266362 @default.
- W1565149579 hasConcept C126322002 @default.
- W1565149579 hasConcept C141071460 @default.
- W1565149579 hasConcept C142724271 @default.
- W1565149579 hasConcept C17744445 @default.
- W1565149579 hasConcept C177713679 @default.
- W1565149579 hasConcept C199539241 @default.
- W1565149579 hasConcept C204787440 @default.
- W1565149579 hasConcept C2777478456 @default.
- W1565149579 hasConcept C2778941218 @default.
- W1565149579 hasConcept C2779473830 @default.
- W1565149579 hasConcept C500440147 @default.
- W1565149579 hasConcept C71924100 @default.
- W1565149579 hasConceptScore W1565149579C126322002 @default.
- W1565149579 hasConceptScore W1565149579C141071460 @default.
- W1565149579 hasConceptScore W1565149579C142724271 @default.
- W1565149579 hasConceptScore W1565149579C17744445 @default.
- W1565149579 hasConceptScore W1565149579C177713679 @default.
- W1565149579 hasConceptScore W1565149579C199539241 @default.
- W1565149579 hasConceptScore W1565149579C204787440 @default.
- W1565149579 hasConceptScore W1565149579C2777478456 @default.
- W1565149579 hasConceptScore W1565149579C2778941218 @default.
- W1565149579 hasConceptScore W1565149579C2779473830 @default.
- W1565149579 hasConceptScore W1565149579C500440147 @default.
- W1565149579 hasConceptScore W1565149579C71924100 @default.
- W1565149579 hasLocation W15651495791 @default.
- W1565149579 hasLocation W15651495792 @default.
- W1565149579 hasOpenAccess W1565149579 @default.
- W1565149579 hasPrimaryLocation W15651495791 @default.
- W1565149579 hasRelatedWork W1986611460 @default.
- W1565149579 hasRelatedWork W2023476217 @default.
- W1565149579 hasRelatedWork W2046708394 @default.
- W1565149579 hasRelatedWork W2061000357 @default.
- W1565149579 hasRelatedWork W2072112550 @default.
- W1565149579 hasRelatedWork W2126431185 @default.
- W1565149579 hasRelatedWork W2277322870 @default.
- W1565149579 hasRelatedWork W2414723751 @default.
- W1565149579 hasRelatedWork W2520362217 @default.
- W1565149579 hasRelatedWork W2537865294 @default.
- W1565149579 hasVolume "60" @default.
- W1565149579 isParatext "false" @default.
- W1565149579 isRetracted "false" @default.
- W1565149579 magId "1565149579" @default.
- W1565149579 workType "article" @default.