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• W1565278318 endingPage "569" @default.
• W1565278318 startingPage "561" @default.
• W1565278318 abstract "A previously undetected subviral particle, designated the 55S particle because of its position in sucrose density gradients, has been found in cytoplasmic extracts of poliovirus-infected cells. It contains no RNA, is composed of equimolar amounts of the structural polypeptides P1AB, P1C, and P1D, and is stable in vitro under a variety of conditions: presence or absence of EDTA, dilution in low- or high-ionic-strength buffers, suspension in buffers up to pH 10, incubation at 37 degrees C, and centrifugation to equilibrium in CsCl gradients (where it bands at a density of 1.285 g/cm3). Conventional pulse-chase experiments show that 55S particles are the products of the assembly of 14S subunits and the precursors of virions. These data led to the formulation of a model of poliovirus morphogenesis in which the conversion of capsomers into 73S empty capsids does not occur directly, but through the formation of an intermediate structure, the 55S particle." @default.
• W1565278318 created "2016-06-24" @default.
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• W1565278318 date "1987-02-01" @default.
• W1565278318 modified "2023-09-23" @default.
• W1565278318 title "Characterization and role in morphogenesis of a new subviral particle (55S) isolated from poliovirus-infected cells" @default.
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• W1565278318 doi "https://doi.org/10.1128/jvi.61.2.561-569.1987" @default.
• W1565278318 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/253981" @default.
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• W1565278318 hasPublicationYear "1987" @default.
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