FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1565281489> ?p ?o ?g. }

• W1565281489 endingPage "189" @default.
• W1565281489 startingPage "178" @default.
• W1565281489 abstract "Understanding the effects of strong static magnetic fields (SMFs) on living organisms is significant in health risk assessment, but underlying mechanisms are largely unknown. In the present study, we determined developmental abnormalities induced by 8.5Tesla (T) SMFs in a well‐established in vivo model organism, Caenorhabditis elegans (C. elegans) . Exposure of C. elegans eggs to 8.5 T SMF resulted in a time‐dependent lifespan decrease, whereas only slight changes were observed upon exposure to 5 T SMF. Although SMF exposure did not alter brood size, development rate and stages were significantly modified by 8.5 T SMF. Germ cell apoptosis dramatically increased upon exposure to 8.5 T SMF in adult worms, as confirmed by ced‐3 and ced‐4 mutants, and could be prevented by concurrent treatment with a free radical scavenger, dimethyl sulfoxide. Compared to wild‐type worms, shorter lifespan and greater numbers of apoptotic cells were observed in abnormal methyl viologen sensitivity‐1 ( mev‐1(kn1) ) nematodes with increased sensitivity to oxidative damage. Furthermore, exposure to 8.5 T SMF increased expression of superoxide dismutase‐3 ( sod‐3 ), which is thought to protect against oxidative stress. However, 8.5 T SMF had minimal effects on lifespans of daf‐2 and daf‐16 mutants, which have compromised insulin/IGF‐1 (insulin‐like growth factors‐1) mediated signaling pathways; this finding was consistent with the expression of these genes in wild‐type worms. Our results indicate that developmental toxicity induced by strong SMF in C. elegans is mediated by oxidative stress and may be regulated by the insulin‐like receptor pathway. Bioelectromagnetics. 36:178–189, 2015. © 2015 Wiley Periodicals, Inc." @default.
• W1565281489 created "2016-06-24" @default.
• W1565281489 creator A5012797389 @default.
• W1565281489 creator A5014920050 @default.
• W1565281489 creator A5015102287 @default.
• W1565281489 creator A5034242696 @default.
• W1565281489 creator A5036983299 @default.
• W1565281489 creator A5053642825 @default.
• W1565281489 creator A5063685824 @default.
• W1565281489 creator A5073216396 @default.
• W1565281489 creator A5089180350 @default.
• W1565281489 creator A5091899965 @default.
• W1565281489 date "2015-03-09" @default.
• W1565281489 modified "2023-10-16" @default.
• W1565281489 title "Developmental abnormality induced by strong static magnetic field in<i>Caenorhabditis elegans</i>" @default.
• W1565281489 cites W1631908837 @default.
• W1565281489 cites W1877188956 @default.
• W1565281489 cites W1922228235 @default.
• W1565281489 cites W1944127002 @default.
• W1565281489 cites W1975672013 @default.
• W1565281489 cites W1984094321 @default.
• W1565281489 cites W1985198044 @default.
• W1565281489 cites W1999626499 @default.
• W1565281489 cites W2004327826 @default.
• W1565281489 cites W2010631293 @default.
• W1565281489 cites W2010800443 @default.
• W1565281489 cites W2021434095 @default.
• W1565281489 cites W2024179549 @default.
• W1565281489 cites W2031643238 @default.
• W1565281489 cites W2033665586 @default.
• W1565281489 cites W2034114408 @default.
• W1565281489 cites W2046390212 @default.
• W1565281489 cites W2050557699 @default.
• W1565281489 cites W2052722944 @default.
• W1565281489 cites W2056015481 @default.
• W1565281489 cites W2058411869 @default.
• W1565281489 cites W2072161932 @default.
• W1565281489 cites W2077249034 @default.
• W1565281489 cites W2080144615 @default.
• W1565281489 cites W2090545557 @default.
• W1565281489 cites W2096541004 @default.
• W1565281489 cites W2104109524 @default.
• W1565281489 cites W2104662939 @default.
• W1565281489 cites W2121168589 @default.
• W1565281489 cites W2127244622 @default.
• W1565281489 cites W2129450287 @default.
• W1565281489 cites W2134810505 @default.
• W1565281489 cites W2135126765 @default.
• W1565281489 cites W2143006697 @default.
• W1565281489 cites W2148125367 @default.
• W1565281489 cites W2152138809 @default.
• W1565281489 cites W2163712834 @default.
• W1565281489 cites W2252622178 @default.
• W1565281489 cites W4206438009 @default.
• W1565281489 cites W4241031272 @default.
• W1565281489 doi "https://doi.org/10.1002/bem.21906" @default.
• W1565281489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25754967" @default.
• W1565281489 hasPublicationYear "2015" @default.
• W1565281489 type Work @default.
• W1565281489 sameAs 1565281489 @default.
• W1565281489 citedByCount "15" @default.
• W1565281489 countsByYear W15652814892017 @default.
• W1565281489 countsByYear W15652814892018 @default.
• W1565281489 countsByYear W15652814892019 @default.
• W1565281489 countsByYear W15652814892020 @default.
• W1565281489 countsByYear W15652814892022 @default.
• W1565281489 countsByYear W15652814892023 @default.
• W1565281489 crossrefType "journal-article" @default.
• W1565281489 hasAuthorship W1565281489A5012797389 @default.
• W1565281489 hasAuthorship W1565281489A5014920050 @default.
• W1565281489 hasAuthorship W1565281489A5015102287 @default.
• W1565281489 hasAuthorship W1565281489A5034242696 @default.
• W1565281489 hasAuthorship W1565281489A5036983299 @default.
• W1565281489 hasAuthorship W1565281489A5053642825 @default.
• W1565281489 hasAuthorship W1565281489A5063685824 @default.
• W1565281489 hasAuthorship W1565281489A5073216396 @default.
• W1565281489 hasAuthorship W1565281489A5089180350 @default.
• W1565281489 hasAuthorship W1565281489A5091899965 @default.
• W1565281489 hasConcept C104317684 @default.
• W1565281489 hasConcept C143065580 @default.
• W1565281489 hasConcept C178790620 @default.
• W1565281489 hasConcept C185592680 @default.
• W1565281489 hasConcept C186256576 @default.
• W1565281489 hasConcept C190283241 @default.
• W1565281489 hasConcept C2775838275 @default.
• W1565281489 hasConcept C2776151105 @default.
• W1565281489 hasConcept C2778004101 @default.
• W1565281489 hasConcept C2778452553 @default.
• W1565281489 hasConcept C2778944004 @default.
• W1565281489 hasConcept C55493867 @default.
• W1565281489 hasConcept C56783068 @default.
• W1565281489 hasConcept C86803240 @default.
• W1565281489 hasConcept C95444343 @default.
• W1565281489 hasConceptScore W1565281489C104317684 @default.
• W1565281489 hasConceptScore W1565281489C143065580 @default.
• W1565281489 hasConceptScore W1565281489C178790620 @default.
• W1565281489 hasConceptScore W1565281489C185592680 @default.
• W1565281489 hasConceptScore W1565281489C186256576 @default.

• next