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- W1565366988 abstract "Because of the multiplicity and saltatory growth pattern associated with central nervous system hemangioblastomas in von Hippel-Lindau (VHL) disease, resection of individual tumors is usually reserved until symptoms occur, to avoid unnecessary surgery over the lifetime of a patient. Brainstem hemangioblastomas in VHL typically cause lower cranial nerve dysfunction, long-tract signs, sensory impairment, and gait abnormalities. The authors report on a 16-year-old girl with VHL who presented with abnormal early satiety resulting in growth and developmental arrest associated with a growing obex hemangioblastoma. Tumor resection resulted in restoration of appetite, with rapid weight gain, growth in stature, and onset of menses. These findings indicate that caudal brainstem-mediated mechanisms have a profound effect on satiety. Moreover, brainstem hemangioblastomas may present with abnormalities in satiety and feeding that can be effectively reversed with resection." @default.
- W1565366988 created "2016-06-24" @default.
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- W1565366988 date "2008-12-01" @default.
- W1565366988 modified "2023-09-25" @default.
- W1565366988 title "Pathological satiety caused by brainstem hemangioblastoma" @default.
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- W1565366988 doi "https://doi.org/10.3171/ped.2008.2.12.397" @default.
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