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- W1565412499 abstract "As a result of X-irradiation of DNA the precursor of a malonaldehyde-like material is formed, which remains covalently bound to DNA. This precursor derives from the damaged deoxyribose moiety of DNA, as indicated by lack of its appearance when free bases or ribonucleotides are irradiated. The precursor can be labeled with tritium by reduction with NaB3H4. The 3H-labeled lesions are excised from the DNA as parts of small oligonucleotides by an enzyme which was partially purified from rat liver extract. The enzyme preparation has high affinity for X-ray-damaged DNA. Its activity has a pH optimum between 8 and 9, requires Mg2+ for activity and is inhibited by Ca2+." @default.
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- W1565412499 date "1974-10-01" @default.
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- W1565412499 title "Enzymatic repair of X-ray-damaged DNA" @default.
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- W1565412499 doi "https://doi.org/10.1016/0005-2787(74)90283-4" @default.
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