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• W1565436444 abstract "The investigation of the underlying causes for the high progesterone (P+) syndrome should presupposefurther studies to more precisely characterise pseudopregnant rabbit does. The purpose of the presentresearch was to examine follicular dynamics in the postovulatory rabbit ovary by means of real-timeB-mode ultrasound scanning. A particular attention was focused upon the population of large-sizedfollicles present through the first 6 days after induced pseudopregnancy, since this follicular category,being steroidogenically active, may be crucial to the survival of the developing CL. Pseudopregnancywas induced in twenty-four hybrid rabbit does caged individually by injection of 100 IU humanchorionic gonadotropin (hCG). Sequential monitoring of dynamic changes in the follicular populationwas performed by ultrasonography on day 0, 2 and 6 of pseudopregnancy (day 0 being the day of hCGinjection). The follicle distribution in ovaries of untreated does (day 0) was marked by approximatelyequal number of small follicles (46.1%±6.7 <2.0 mm) and large follicles (54.4%±6.1 ≥2.0 mm).However, at 2 days after injection of an ovulatory dose of hCG, the large follicles population wasmarkedly depleted with only 10.2%±0.9 of the follicles present classified as large. The ovulation rateaveraged 10.8±0.7 per rabbit. By day 6 of pseudopregnancy the size distribution showed that arepopulation of the ovary with large follicles occurred with 71.3%±6.8 in this category. The largefollicles lost at ovulation had apparently been replaced by the time of luteal estrogen dependence atday 6 of pseudopregnancy. The results presented in this report, demonstrating that the rabbit ovary isdepleted of large follicles following ovulation but that large, steroidogenically active follicles areagain present by day 6, could be considered as a preliminary step to understand what mechanismsprotect the CL from luteolysis until day 6 of pseudopregnancy, when CL shift from completerefractoriness to partial and complete responsiveness to PGF2α treatment. Since little is known aboutwhat factors effectively trigger luteolysis in normal, physiological conditions as well as whatmechanisms protect CL from luteolysis in the first days of pseudopregnancy, the innovative and noninvasiveapproach supplied by the real-time ultrasonography could represent an additional tool forinvestigation." @default.
• W1565436444 created "2016-06-24" @default.
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• W1565436444 date "2008-01-01" @default.
• W1565436444 modified "2023-09-23" @default.
• W1565436444 title "Ultrasound evaluation of ovarian follicular dynamics during early pseudopregnancy as a tool to inquire into the high progesterone (P+) syndrome of rabbit does" @default.
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