FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1565557462> ?p ?o ?g. }

• W1565557462 endingPage "11705" @default.
• W1565557462 startingPage "11697" @default.
• W1565557462 abstract "Magnesium transport across sarcoplasmic reticulum (SR) vesicles was investigated in reaction mixtures of various composition using antipyrylazo III or arsenazo I to monitor extravesicular free Mg2+. The half-time of passive Mg2+ efflux from Mg2+-loaded SR was 100 s in 100 mM KCl, 150 S in 100 mM K gluconate, and 370 S in either 100 mM Tris methanesulfonate or 200 mM sucrose solutions. The concentration and time course of Mg2+ released into the medium was also measured during ATP-dependent Ca2+ uptake by SR. In reaction mixtures containing up to 3 mM Mg2+, small changes in free magnesium of 10 microM or less were accurately detected without interference from changes in free Ca2+ of up to 100 microM. Three experimental protocols were used to determine whether the increase of free [Mg2+] in the medium after an addition of ATP was due to Mg2+ dissociated from ATP following ATP hydrolysis or to Mg2+ translocation from inside to outside of the vesicles. 1) In the presence of ATP-regenerating systems which maintained constant ATP to ADP ratios and normal rates of active Ca2+ uptake, the increase of Mg2+ in the medium was negligible. 2) Mg2+ released during ATP-dependent Ca2+ uptake by SR was similar to that observed during ATP hydrolysis catalyzed by apyrase, in the absence of SR. 3) In SR lysed with Triton X-100 such that Ca2+ transport was uncoupled from ATPase activity, the rate and amount of Mg2+ release was greater than that observed during ATP-dependent Ca2+ uptake by intact vesicles. Taken together, the results indicate that passive fluxes of Mg2+ across SR membranes are 10 times faster than those of Ca2+ and that Mg2+ is not counter-transported during active Ca2+ accumulation by SR even in reaction mixtures containing minimal concentrations of membrane permeable ions that could be rapidly exchanged or cotransported with Ca2+ (e.g. K+ or Cl-)." @default.
• W1565557462 created "2016-06-24" @default.
• W1565557462 creator A5025283915 @default.
• W1565557462 creator A5068618541 @default.
• W1565557462 date "1985-09-01" @default.
• W1565557462 modified "2023-09-27" @default.
• W1565557462 title "Magnesium permeability of sarcoplasmic reticulum. Mg2+ is not countertransported during ATP-dependent Ca2+ uptake by sarcoplasmic reticulum." @default.
• W1565557462 cites W1510897113 @default.
• W1565557462 cites W1549532521 @default.
• W1565557462 cites W1594707751 @default.
• W1565557462 cites W1632253085 @default.
• W1565557462 cites W1653768435 @default.
• W1565557462 cites W1775749144 @default.
• W1565557462 cites W1830876683 @default.
• W1565557462 cites W1970231487 @default.
• W1565557462 cites W1977806355 @default.
• W1565557462 cites W1980328732 @default.
• W1565557462 cites W1981272477 @default.
• W1565557462 cites W1982302456 @default.
• W1565557462 cites W1997470717 @default.
• W1565557462 cites W2000207690 @default.
• W1565557462 cites W2012111248 @default.
• W1565557462 cites W2037598944 @default.
• W1565557462 cites W2048713667 @default.
• W1565557462 cites W2053584696 @default.
• W1565557462 cites W2067706502 @default.
• W1565557462 cites W2080434177 @default.
• W1565557462 cites W2082036967 @default.
• W1565557462 cites W2114439837 @default.
• W1565557462 cites W2170229531 @default.
• W1565557462 cites W2270586006 @default.
• W1565557462 cites W2078792694 @default.
• W1565557462 doi "https://doi.org/10.1016/s0021-9258(17)39086-5" @default.
• W1565557462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3930482" @default.
• W1565557462 hasPublicationYear "1985" @default.
• W1565557462 type Work @default.
• W1565557462 sameAs 1565557462 @default.
• W1565557462 citedByCount "8" @default.
• W1565557462 crossrefType "journal-article" @default.
• W1565557462 hasAuthorship W1565557462A5025283915 @default.
• W1565557462 hasAuthorship W1565557462A5068618541 @default.
• W1565557462 hasBestOaLocation W15655574621 @default.
• W1565557462 hasConcept C113217602 @default.
• W1565557462 hasConcept C120882062 @default.
• W1565557462 hasConcept C12554922 @default.
• W1565557462 hasConcept C126322002 @default.
• W1565557462 hasConcept C158617107 @default.
• W1565557462 hasConcept C178790620 @default.
• W1565557462 hasConcept C185592680 @default.
• W1565557462 hasConcept C190712762 @default.
• W1565557462 hasConcept C41625074 @default.
• W1565557462 hasConcept C519063684 @default.
• W1565557462 hasConcept C543218039 @default.
• W1565557462 hasConcept C55493867 @default.
• W1565557462 hasConcept C71924100 @default.
• W1565557462 hasConcept C86803240 @default.
• W1565557462 hasConceptScore W1565557462C113217602 @default.
• W1565557462 hasConceptScore W1565557462C120882062 @default.
• W1565557462 hasConceptScore W1565557462C12554922 @default.
• W1565557462 hasConceptScore W1565557462C126322002 @default.
• W1565557462 hasConceptScore W1565557462C158617107 @default.
• W1565557462 hasConceptScore W1565557462C178790620 @default.
• W1565557462 hasConceptScore W1565557462C185592680 @default.
• W1565557462 hasConceptScore W1565557462C190712762 @default.
• W1565557462 hasConceptScore W1565557462C41625074 @default.
• W1565557462 hasConceptScore W1565557462C519063684 @default.
• W1565557462 hasConceptScore W1565557462C543218039 @default.
• W1565557462 hasConceptScore W1565557462C55493867 @default.
• W1565557462 hasConceptScore W1565557462C71924100 @default.
• W1565557462 hasConceptScore W1565557462C86803240 @default.
• W1565557462 hasIssue "21" @default.
• W1565557462 hasLocation W15655574621 @default.
• W1565557462 hasOpenAccess W1565557462 @default.
• W1565557462 hasPrimaryLocation W15655574621 @default.
• W1565557462 hasRelatedWork W154292401 @default.
• W1565557462 hasRelatedWork W1821931995 @default.
• W1565557462 hasRelatedWork W1986273190 @default.
• W1565557462 hasRelatedWork W2024858633 @default.
• W1565557462 hasRelatedWork W2089232336 @default.
• W1565557462 hasRelatedWork W2138310843 @default.
• W1565557462 hasRelatedWork W2412710947 @default.
• W1565557462 hasRelatedWork W2434512304 @default.
• W1565557462 hasRelatedWork W2464779735 @default.
• W1565557462 hasRelatedWork W2474136078 @default.
• W1565557462 hasVolume "260" @default.
• W1565557462 isParatext "false" @default.
• W1565557462 isRetracted "false" @default.
• W1565557462 magId "1565557462" @default.
• W1565557462 workType "article" @default.