Matches in SemOpenAlex for { <https://semopenalex.org/work/W1565624900> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1565624900 endingPage "88" @default.
- W1565624900 startingPage "75" @default.
- W1565624900 abstract "Liver transplantation (OLT) is indicated in patients with severe and irreversible acute or chronic liver disease without alternative therapy and in the absence of contraindications. Indications for OLT can be grouped in four categories, namely cirrhosis, fulminant hepatitis, malignant hepatic tumors and liver-based genetic defects that trigger damage of other organs. Patients with cirrhosis should be referred for OLT after the onset of any of the major complications or coagulopathy. Early referral is crucial in fulminant hepatitis due to the high mortality with medical therapy and the unpredictable nature of this condition. Ideal timing for OLT is the moment in the natural history of the disease when the expected survival of patients on the waiting list is higher with than without OLT. Recent data suggest that maximal benefit of OLT is obtained in patients with a MELD score >15. However, in some cases with no imminent risk of death, OLT is indicated to improve quality of life or to prevent contraindications such as progression of hepatocellular carcinoma. At present, there is a marked disproportion between the number of donors available and the growing number of patients listed worldwide, which in turn has resulted in prolongation of the time-interval to OLT and waitlist mortality. The rationale of allocation systems utilizing the MELD score is to prioritize on the waiting list patients with severe liver dysfunction (the sickest first) and those with hepatocellular carcinoma who may loose the benefits of OLT when waitlist time exceeds eight months." @default.
- W1565624900 created "2016-06-24" @default.
- W1565624900 creator A5039908032 @default.
- W1565624900 creator A5088252677 @default.
- W1565624900 date "2008-03-01" @default.
- W1565624900 modified "2023-09-27" @default.
- W1565624900 title "[Indications and timing of liver transplantation]." @default.
- W1565624900 cites W1583922175 @default.
- W1565624900 cites W1608215573 @default.
- W1565624900 cites W1964537031 @default.
- W1565624900 cites W1970561853 @default.
- W1565624900 cites W2001137775 @default.
- W1565624900 cites W2001202402 @default.
- W1565624900 cites W2003709460 @default.
- W1565624900 cites W2008254973 @default.
- W1565624900 cites W2012477397 @default.
- W1565624900 cites W2014372043 @default.
- W1565624900 cites W2016024882 @default.
- W1565624900 cites W2016237283 @default.
- W1565624900 cites W2018182967 @default.
- W1565624900 cites W2018629159 @default.
- W1565624900 cites W2020740200 @default.
- W1565624900 cites W2027988867 @default.
- W1565624900 cites W2033755132 @default.
- W1565624900 cites W2035226846 @default.
- W1565624900 cites W2037263447 @default.
- W1565624900 cites W2038385804 @default.
- W1565624900 cites W2042205558 @default.
- W1565624900 cites W2059819368 @default.
- W1565624900 cites W2060123467 @default.
- W1565624900 cites W2060314227 @default.
- W1565624900 cites W2066967987 @default.
- W1565624900 cites W2067210852 @default.
- W1565624900 cites W2068267552 @default.
- W1565624900 cites W2069243984 @default.
- W1565624900 cites W2069906948 @default.
- W1565624900 cites W2070870744 @default.
- W1565624900 cites W2071282740 @default.
- W1565624900 cites W2073693064 @default.
- W1565624900 cites W2073793678 @default.
- W1565624900 cites W2079169996 @default.
- W1565624900 cites W2084074511 @default.
- W1565624900 cites W2084199501 @default.
- W1565624900 cites W2089911610 @default.
- W1565624900 cites W2102063072 @default.
- W1565624900 cites W2102301083 @default.
- W1565624900 cites W2116234733 @default.
- W1565624900 cites W2122622542 @default.
- W1565624900 cites W2136220561 @default.
- W1565624900 cites W2140396673 @default.
- W1565624900 cites W2146085139 @default.
- W1565624900 cites W2147292430 @default.
- W1565624900 cites W2160196408 @default.
- W1565624900 cites W2161109243 @default.
- W1565624900 cites W2169486708 @default.
- W1565624900 cites W2315027248 @default.
- W1565624900 cites W2983266270 @default.
- W1565624900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18533359" @default.
- W1565624900 hasPublicationYear "2008" @default.
- W1565624900 type Work @default.
- W1565624900 sameAs 1565624900 @default.
- W1565624900 citedByCount "2" @default.
- W1565624900 countsByYear W15656249002014 @default.
- W1565624900 crossrefType "journal-article" @default.
- W1565624900 hasAuthorship W1565624900A5039908032 @default.
- W1565624900 hasAuthorship W1565624900A5088252677 @default.
- W1565624900 hasConcept C138885662 @default.
- W1565624900 hasConcept C15708023 @default.
- W1565624900 hasConcept C71924100 @default.
- W1565624900 hasConceptScore W1565624900C138885662 @default.
- W1565624900 hasConceptScore W1565624900C15708023 @default.
- W1565624900 hasConceptScore W1565624900C71924100 @default.
- W1565624900 hasIssue "1" @default.
- W1565624900 hasLocation W15656249001 @default.
- W1565624900 hasOpenAccess W1565624900 @default.
- W1565624900 hasPrimaryLocation W15656249001 @default.
- W1565624900 hasVolume "38" @default.
- W1565624900 isParatext "false" @default.
- W1565624900 isRetracted "false" @default.
- W1565624900 magId "1565624900" @default.
- W1565624900 workType "article" @default.