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- W1565628449 abstract "Objectives: To synthesize, characterize and evaluate antimicrobial properties of some benzenesulfonamide based bipyrazole. Methods: The benzenesulfonamide based bipyrazole 1a-d & 2a-f have been synthesized by the reaction between 1-[1-aryl / (benzothiazol-2-yl)-5-hydroxy-3-methylpyrazol-4-yl]butane-1,3-diones 5 and 2-hydrazinobenzothiazoles or Aryl hydrazines 3 . The structures of these compounds have been characterized from the rigorous analysis of their IR, 1 H-NMR, HRMS and elemental analysis. These compounds were screened for their anti-microbial activity. Results: The results revealed that compounds 1a , 2b and 2f exhibited good antibacterial activity and 1b , 1c , 2a , and 2d showed moderate antibacterial activity as compared with standard drug Ofloxacin. Conclusion: This study provides the simple method for the synthesis of new benzenzenesulfonamide based bipyrazoles which plays important role in numerous bioactive compounds." @default.
- W1565628449 created "2016-06-24" @default.
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- W1565628449 date "2014-10-01" @default.
- W1565628449 modified "2023-09-26" @default.
- W1565628449 title "SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDY OF SOME BENZENESULFONAMIDE BASED BIPYRAZOLES" @default.
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