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- W1565791818 abstract "Publisher Summary The chondroitin sulfates (CSs) are, as most other glycosaminoglycans (GAGs), linear polysaccharides in which a simple disaccharide repeating unit has been modified postpolymerization to give a more complex and heterogeneous set of structures. The significance of CS to the structural integrity of extracellular matrix has long been recognized and in that context, the three‐dimensional structures of CS and whole proteoglycans (PGs) of which they are a part have been the subject of classic studies. CS has been recognized in diverse structural roles, and it has been shown to link two proteins together. However, CS may also take part in specific interactions with proteins through specific oligosaccharide sequences, some of which are highly sulfated, and the significance of these interactions for the growth and development of tissues has inspired structural determinations for these active structures. Experimental studies of protein–CS complex structures are now appearing and theoretical and experimental approaches have been applied to CS with interesting results." @default.
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- W1565791818 date "2006-01-01" @default.
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- W1565791818 title "Progress in the Structural Biology of Chondroitin Sulfate" @default.
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- W1565791818 doi "https://doi.org/10.1016/s1054-3589(05)53004-7" @default.
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