FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566144444> ?p ?o ?g. }

• W1566144444 abstract "Background Extravasation injury, a complication commonly seen in the neonatal intensive care unit, can result in scarring with cosmetic and functional sequelae. A wide variety of treatments are available, including subcutaneous irrigation with saline (with or without hyaluronidase), liposuction, use of specific antidotes, topical applications, and normal wound care with dry or wet dressings. All such treatments aim to prevent or reduce the severity of complications. Objectives Primary objective To compare the efficacy and safety of saline irrigation or saline irrigation with prior hyaluronidase infiltration versus no intervention or normal wound care for tissue healing in neonates with extravasation injury. Secondary objectives To evaluate by subgroup analysis of controlled trials the influence of type of extravasate, timing of irrigation following extravasation, and postmenstrual age (PMA) of the neonate at the time of injury on outcomes and adverse effects. Specifically, we planned to perform subgroup analysis for the primary outcome, if appropriate, by examining: 1. time to irrigation from identified extravasation injury (< 1 hour or ≥ 1 hour); 2. type of extravasate (parenteral nutrition fluid or other fluids or medications); 3. amount of saline used (< 500 mL or ≥ 500 mL); and 4. PMA at injury (< 37 completed weeks or ≥ 37 completed weeks). Search methods We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 1), MEDLINE via PubMed (1966 to 2 February 2017), Embase (1980 to 2 February 2017), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; 1982 to 2 February 2017). We also searched clinical trial databases, conference proceedings, and reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials. We used the Google Scholar search tool for reverse citations of relevant articles. Selection criteria Randomised controlled trials (RCTs) and quasi‐randomised controlled trials comparing saline irrigation with or without hyaluronidase infiltration versus no intervention or normal wound care for the management of extravasation injury in neonates. Data collection and analysis Three review authors independently reviewed and identified articles for possible inclusion in this review. We used the GRADE approach to assess the quality of evidence. Main results We found no eligible studies. Our search revealed 10 case reports or case series describing successful outcomes with different interventions for this condition. Authors' conclusions To date, no RCTs have examined the effects of saline irrigation with or without prior hyaluronidase infiltration for management of extravasation injury in neonates. Saline irrigation is frequently reported in the literature as an intervention for management of extravasation injury in neonates. Research should focus first on evaluating the efficacy and safety of this intervention through RCTs. It will also be important for investigators to determine effect size by examining the timing of the intervention, the nature of the infusate, and severity of injury at the time of intervention." @default.
• W1566144444 created "2016-06-24" @default.
• W1566144444 creator A5050910750 @default.
• W1566144444 creator A5060429026 @default.
• W1566144444 creator A5072685237 @default.
• W1566144444 date "2017-07-19" @default.
• W1566144444 modified "2023-10-18" @default.
• W1566144444 title "Saline irrigation for the management of skin extravasation injury in neonates" @default.
• W1566144444 cites W166564771 @default.
• W1566144444 cites W1747531399 @default.
• W1566144444 cites W1948202894 @default.
• W1566144444 cites W1972129531 @default.
• W1566144444 cites W1975235719 @default.
• W1566144444 cites W1993472621 @default.
• W1566144444 cites W1993495658 @default.
• W1566144444 cites W1999006290 @default.
• W1566144444 cites W2011048923 @default.
• W1566144444 cites W2013179857 @default.
• W1566144444 cites W2016909352 @default.
• W1566144444 cites W2020969440 @default.
• W1566144444 cites W2021879700 @default.
• W1566144444 cites W2032510931 @default.
• W1566144444 cites W2036823261 @default.
• W1566144444 cites W2047102248 @default.
• W1566144444 cites W2050290554 @default.
• W1566144444 cites W2078613856 @default.
• W1566144444 cites W2079292264 @default.
• W1566144444 cites W2080565347 @default.
• W1566144444 cites W2110548165 @default.
• W1566144444 cites W2126491713 @default.
• W1566144444 cites W2157765667 @default.
• W1566144444 cites W2158168165 @default.
• W1566144444 cites W2262860441 @default.
• W1566144444 cites W2323801284 @default.
• W1566144444 cites W2325615336 @default.
• W1566144444 cites W2335753077 @default.
• W1566144444 cites W2396194283 @default.
• W1566144444 cites W3148880446 @default.
• W1566144444 cites W4206827162 @default.
• W1566144444 cites W4243516812 @default.
• W1566144444 cites W4243865968 @default.
• W1566144444 cites W58788346 @default.
• W1566144444 cites W90931096 @default.
• W1566144444 doi "https://doi.org/10.1002/14651858.cd008404.pub3" @default.
• W1566144444 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6483149" @default.
• W1566144444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28724193" @default.
• W1566144444 hasPublicationYear "2017" @default.
• W1566144444 type Work @default.
• W1566144444 sameAs 1566144444 @default.
• W1566144444 citedByCount "9" @default.
• W1566144444 countsByYear W15661444442018 @default.
• W1566144444 countsByYear W15661444442019 @default.
• W1566144444 countsByYear W15661444442021 @default.
• W1566144444 countsByYear W15661444442022 @default.
• W1566144444 countsByYear W15661444442023 @default.
• W1566144444 crossrefType "journal-article" @default.
• W1566144444 hasAuthorship W1566144444A5050910750 @default.
• W1566144444 hasAuthorship W1566144444A5060429026 @default.
• W1566144444 hasAuthorship W1566144444A5072685237 @default.
• W1566144444 hasBestOaLocation W15661444442 @default.
• W1566144444 hasConcept C126322002 @default.
• W1566144444 hasConcept C141071460 @default.
• W1566144444 hasConcept C142724271 @default.
• W1566144444 hasConcept C197934379 @default.
• W1566144444 hasConcept C2777397205 @default.
• W1566144444 hasConcept C2779540182 @default.
• W1566144444 hasConcept C3017567848 @default.
• W1566144444 hasConcept C42219234 @default.
• W1566144444 hasConcept C71924100 @default.
• W1566144444 hasConceptScore W1566144444C126322002 @default.
• W1566144444 hasConceptScore W1566144444C141071460 @default.
• W1566144444 hasConceptScore W1566144444C142724271 @default.
• W1566144444 hasConceptScore W1566144444C197934379 @default.
• W1566144444 hasConceptScore W1566144444C2777397205 @default.
• W1566144444 hasConceptScore W1566144444C2779540182 @default.
• W1566144444 hasConceptScore W1566144444C3017567848 @default.
• W1566144444 hasConceptScore W1566144444C42219234 @default.
• W1566144444 hasConceptScore W1566144444C71924100 @default.
• W1566144444 hasIssue "7" @default.
• W1566144444 hasLocation W15661444441 @default.
• W1566144444 hasLocation W15661444442 @default.
• W1566144444 hasLocation W15661444443 @default.
• W1566144444 hasLocation W15661444444 @default.
• W1566144444 hasOpenAccess W1566144444 @default.
• W1566144444 hasPrimaryLocation W15661444441 @default.
• W1566144444 hasRelatedWork W2003938723 @default.
• W1566144444 hasRelatedWork W2029267180 @default.
• W1566144444 hasRelatedWork W2047967234 @default.
• W1566144444 hasRelatedWork W2118496982 @default.
• W1566144444 hasRelatedWork W2439875401 @default.
• W1566144444 hasRelatedWork W2889975111 @default.
• W1566144444 hasRelatedWork W2920970278 @default.
• W1566144444 hasRelatedWork W2979527601 @default.
• W1566144444 hasRelatedWork W3006711529 @default.
• W1566144444 hasRelatedWork W2525756941 @default.
• W1566144444 hasVolume "2017" @default.
• W1566144444 isParatext "false" @default.
• W1566144444 isRetracted "false" @default.
• W1566144444 magId "1566144444" @default.
• W1566144444 workType "article" @default.