Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566146140> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1566146140 endingPage "404" @default.
- W1566146140 startingPage "399" @default.
- W1566146140 abstract "Noninvasive molecular targeting in living subjects is highly demanded for better understanding of such diverse topics as the efficient delivery of drugs, genes, or radionuclides for the diagnosis or treatment of diseases. Progress in molecular biology, genetic engineering and polymer chemistry provides various tools to target molecules and cells in vivo. We used chitosan as a polymer, and as a radionuclide. We developed chitosan to target asialoglycoprotein receptors for nuclear imaging. We also developed to target inflammatory cells, which was more effective than for imaging inflammatory lesions. For an effective delivery of molecules, a longer circulation time is needed. We found that around 10% PEGylation was most effective to prolong the circulation time of liposomes for nuclear imaging of liposomes in rats. Using various characteristics of molecules, we can deliver drugs into targets more effectively. We found that biodegradable pullulan-derivatives are retained in tumor tissue in response to extracellular ion-strength. For the trafficking of various cells or bacteria in an intact animal, we used optical imaging techniques or radiolabeled cells. We monitored tumor-targeting bacteria by bioluminescent imaging techniques, dentritic cells by radiolabeling and neuronal stem cells by sodium-iodide symporter reporter gene imaging. In summary, we introduced recent achievements of molecular nuclear imaging technologies in targeting receptors for hepatocyte or inflammatory cells and in trafficking bacterial, immune and stem cells using molecular nuclear imaging techniques." @default.
- W1566146140 created "2016-06-24" @default.
- W1566146140 creator A5017366073 @default.
- W1566146140 creator A5079729400 @default.
- W1566146140 creator A5082687532 @default.
- W1566146140 date "2006-07-01" @default.
- W1566146140 modified "2023-09-23" @default.
- W1566146140 title "MOLECULAR NUCLEAR IMAGING FOR TARGETING AND TRAFFICKING" @default.
- W1566146140 cites W1551672400 @default.
- W1566146140 cites W1969532639 @default.
- W1566146140 cites W2003841370 @default.
- W1566146140 cites W2072955125 @default.
- W1566146140 cites W2254642003 @default.
- W1566146140 cites W2271745928 @default.
- W1566146140 cites W2294288654 @default.
- W1566146140 hasPublicationYear "2006" @default.
- W1566146140 type Work @default.
- W1566146140 sameAs 1566146140 @default.
- W1566146140 citedByCount "0" @default.
- W1566146140 crossrefType "journal-article" @default.
- W1566146140 hasAuthorship W1566146140A5017366073 @default.
- W1566146140 hasAuthorship W1566146140A5079729400 @default.
- W1566146140 hasAuthorship W1566146140A5082687532 @default.
- W1566146140 hasConcept C104317684 @default.
- W1566146140 hasConcept C111599444 @default.
- W1566146140 hasConcept C120405084 @default.
- W1566146140 hasConcept C12554922 @default.
- W1566146140 hasConcept C135983454 @default.
- W1566146140 hasConcept C136339569 @default.
- W1566146140 hasConcept C149011108 @default.
- W1566146140 hasConcept C150903083 @default.
- W1566146140 hasConcept C185592680 @default.
- W1566146140 hasConcept C207001950 @default.
- W1566146140 hasConcept C2780616701 @default.
- W1566146140 hasConcept C28328180 @default.
- W1566146140 hasConcept C2987346553 @default.
- W1566146140 hasConcept C2989005 @default.
- W1566146140 hasConcept C55493867 @default.
- W1566146140 hasConcept C71924100 @default.
- W1566146140 hasConcept C86803240 @default.
- W1566146140 hasConcept C95444343 @default.
- W1566146140 hasConceptScore W1566146140C104317684 @default.
- W1566146140 hasConceptScore W1566146140C111599444 @default.
- W1566146140 hasConceptScore W1566146140C120405084 @default.
- W1566146140 hasConceptScore W1566146140C12554922 @default.
- W1566146140 hasConceptScore W1566146140C135983454 @default.
- W1566146140 hasConceptScore W1566146140C136339569 @default.
- W1566146140 hasConceptScore W1566146140C149011108 @default.
- W1566146140 hasConceptScore W1566146140C150903083 @default.
- W1566146140 hasConceptScore W1566146140C185592680 @default.
- W1566146140 hasConceptScore W1566146140C207001950 @default.
- W1566146140 hasConceptScore W1566146140C2780616701 @default.
- W1566146140 hasConceptScore W1566146140C28328180 @default.
- W1566146140 hasConceptScore W1566146140C2987346553 @default.
- W1566146140 hasConceptScore W1566146140C2989005 @default.
- W1566146140 hasConceptScore W1566146140C55493867 @default.
- W1566146140 hasConceptScore W1566146140C71924100 @default.
- W1566146140 hasConceptScore W1566146140C86803240 @default.
- W1566146140 hasConceptScore W1566146140C95444343 @default.
- W1566146140 hasIssue "5" @default.
- W1566146140 hasLocation W15661461401 @default.
- W1566146140 hasOpenAccess W1566146140 @default.
- W1566146140 hasPrimaryLocation W15661461401 @default.
- W1566146140 hasRelatedWork W2047441093 @default.
- W1566146140 hasRelatedWork W2049541843 @default.
- W1566146140 hasRelatedWork W2058747498 @default.
- W1566146140 hasRelatedWork W2060256091 @default.
- W1566146140 hasRelatedWork W2115264660 @default.
- W1566146140 hasRelatedWork W2160725302 @default.
- W1566146140 hasRelatedWork W2389119193 @default.
- W1566146140 hasRelatedWork W2559714456 @default.
- W1566146140 hasRelatedWork W2725185907 @default.
- W1566146140 hasRelatedWork W2808671462 @default.
- W1566146140 hasRelatedWork W2925340933 @default.
- W1566146140 hasRelatedWork W2951141760 @default.
- W1566146140 hasRelatedWork W2998292126 @default.
- W1566146140 hasRelatedWork W307372272 @default.
- W1566146140 hasRelatedWork W3094477728 @default.
- W1566146140 hasRelatedWork W3121722193 @default.
- W1566146140 hasRelatedWork W830650649 @default.
- W1566146140 hasRelatedWork W2041660493 @default.
- W1566146140 hasRelatedWork W2298451068 @default.
- W1566146140 hasRelatedWork W2880856163 @default.
- W1566146140 hasVolume "38" @default.
- W1566146140 isParatext "false" @default.
- W1566146140 isRetracted "false" @default.
- W1566146140 magId "1566146140" @default.
- W1566146140 workType "article" @default.