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• W1566149917 startingPage "324" @default.
• W1566149917 abstract "Target-mediated drug disposition (TMDD) is the phenomenon in which a drug binds with high affinity to its pharmacological target site (such as a receptor) to such an extent that this affects its pharmacokinetic characteristics.1 The aim of this Tutorial is to provide an introductory guide to the mathematical aspects of TMDD models for pharmaceutical researchers. Examples of Berkeley Madonna2 code for some models discussed in this Tutorial are provided in the Supplementary Materials." @default.
• W1566149917 created "2016-06-24" @default.
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• W1566149917 date "2015-06-01" @default.
• W1566149917 modified "2023-10-14" @default.
• W1566149917 title "A Tutorial on Target-Mediated Drug Disposition (TMDD) Models" @default.
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• W1566149917 doi "https://doi.org/10.1002/psp4.41" @default.
• W1566149917 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4505827" @default.
• W1566149917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26225261" @default.
• W1566149917 hasPublicationYear "2015" @default.
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