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- W1566165926 abstract "Abstract That horses possessing natural antitoxin in their blood produce antitoxin readily is well known by workers (Hitchens and Tingley, Hida, Glenny, Wadsworth, Sordelli, Ramon, etc.) in this field. Park and Zingher pointed out that persons yielding negative Schick tests respond to toxin-antitoxin injections with the production of antitoxin more readily than those who react in a positive manner. In the selection of such naturally immune horses for the purpose of immunization a trial bleeding is usually taken and the serum is tested for natural antitoxin by Römer's cutaneous method or Ehrlich's subcutaneous method. Hitchens and Tingley injected 0.2 cc. diphtheria toxin, equaling 3 m.l.d.'s for 250 gram guinea pigs, into the conjunctiva of one eye of horses under examination for the purposes of immunization, and found that many yielded negative tests read at the end of forty-eight hours, indicating the presence of natural diphtheria-antitoxin in the blood of normal horses." @default.
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- W1566165926 date "1929-12-01" @default.
- W1566165926 modified "2023-09-25" @default.
- W1566165926 title "Schick Test as Applied to the Selection of Horses for the Production of Diphtheria Antitoxin" @default.
- W1566165926 doi "https://doi.org/10.4049/jimmunol.17.6.523" @default.
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