Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566200162> ?p ?o ?g. }
- W1566200162 endingPage "52" @default.
- W1566200162 startingPage "40" @default.
- W1566200162 abstract "Abstract Triatomines (Hemiptera: Reduviidae) are obligate hematophagous insects. They are of medical importance because they are vectors of Trypanosoma cruzi, the causative agent of Chagas disease in the Americas. In recent years, the RNA interference (RNAi) technology has emerged as a practical and useful alternative means of studying gene function in insects, including triatomine bugs. RNAi research in triatomines is still in its early stages, several issues still need to be elucidated, including the description of the molecules involved in the RNAi machinery and aspects related to phenotype evaluation and persistence of the knockdown in different tissues and organs. This review considers recent applications of RNAi to triatomine research, describing the major methods that have been applied during the knockdown process such as the double-stranded RNA delivery mechanism (injection, microinjection, or ingestion) and the phenotype characterization (mRNA and target protein levels) in studies conducted with the intent to provide greater insights into the biology of these insects. In addition to the characterization of insect biomolecules, some with biopharmacological potential, RNAi may provide a new view of the interaction between triatomine and trypanosomatids, enabling the development of new measures for vector control and transmission of the parasite." @default.
- W1566200162 created "2016-06-24" @default.
- W1566200162 creator A5044353070 @default.
- W1566200162 creator A5057924572 @default.
- W1566200162 creator A5059925235 @default.
- W1566200162 creator A5066058396 @default.
- W1566200162 creator A5081941115 @default.
- W1566200162 date "2012-07-30" @default.
- W1566200162 modified "2023-09-25" @default.
- W1566200162 title "Application of RNA interference in triatomine (Hemiptera: Reduviidae) studies" @default.
- W1566200162 cites W1548528591 @default.
- W1566200162 cites W1582880096 @default.
- W1566200162 cites W1647075334 @default.
- W1566200162 cites W1965389967 @default.
- W1566200162 cites W1966543080 @default.
- W1566200162 cites W1971746827 @default.
- W1566200162 cites W1973760024 @default.
- W1566200162 cites W1976879480 @default.
- W1566200162 cites W1977302094 @default.
- W1566200162 cites W1978290762 @default.
- W1566200162 cites W1982388263 @default.
- W1566200162 cites W1985692378 @default.
- W1566200162 cites W1987120649 @default.
- W1566200162 cites W1988007522 @default.
- W1566200162 cites W1989313716 @default.
- W1566200162 cites W1989454102 @default.
- W1566200162 cites W1989552463 @default.
- W1566200162 cites W1990027679 @default.
- W1566200162 cites W1992437223 @default.
- W1566200162 cites W1994709452 @default.
- W1566200162 cites W2000001825 @default.
- W1566200162 cites W2001256177 @default.
- W1566200162 cites W2001997232 @default.
- W1566200162 cites W2004271888 @default.
- W1566200162 cites W2008716207 @default.
- W1566200162 cites W2014861681 @default.
- W1566200162 cites W2016866607 @default.
- W1566200162 cites W2021805889 @default.
- W1566200162 cites W2026350159 @default.
- W1566200162 cites W2029743681 @default.
- W1566200162 cites W2035840279 @default.
- W1566200162 cites W2037042953 @default.
- W1566200162 cites W2037169799 @default.
- W1566200162 cites W2038544330 @default.
- W1566200162 cites W2042170238 @default.
- W1566200162 cites W2042915315 @default.
- W1566200162 cites W2043641895 @default.
- W1566200162 cites W2048817002 @default.
- W1566200162 cites W2054156026 @default.
- W1566200162 cites W2055918431 @default.
- W1566200162 cites W2065234600 @default.
- W1566200162 cites W2072457310 @default.
- W1566200162 cites W2073840770 @default.
- W1566200162 cites W2074898833 @default.
- W1566200162 cites W2075020878 @default.
- W1566200162 cites W2075615690 @default.
- W1566200162 cites W2078313173 @default.
- W1566200162 cites W2079902244 @default.
- W1566200162 cites W2085171492 @default.
- W1566200162 cites W2086216118 @default.
- W1566200162 cites W2096018896 @default.
- W1566200162 cites W2108284976 @default.
- W1566200162 cites W2114582526 @default.
- W1566200162 cites W2115171772 @default.
- W1566200162 cites W2117675834 @default.
- W1566200162 cites W2117991391 @default.
- W1566200162 cites W2120306397 @default.
- W1566200162 cites W2121934903 @default.
- W1566200162 cites W2124791602 @default.
- W1566200162 cites W2128702749 @default.
- W1566200162 cites W2143427287 @default.
- W1566200162 cites W2145940942 @default.
- W1566200162 cites W2149221950 @default.
- W1566200162 cites W2150972545 @default.
- W1566200162 cites W2152993806 @default.
- W1566200162 cites W2153465572 @default.
- W1566200162 cites W2153471314 @default.
- W1566200162 cites W2158626657 @default.
- W1566200162 cites W2162674498 @default.
- W1566200162 cites W2162824156 @default.
- W1566200162 cites W2167929526 @default.
- W1566200162 cites W2168486884 @default.
- W1566200162 cites W2170949754 @default.
- W1566200162 cites W2171893553 @default.
- W1566200162 cites W2312467527 @default.
- W1566200162 cites W4211039187 @default.
- W1566200162 doi "https://doi.org/10.1111/j.1744-7917.2012.01540.x" @default.
- W1566200162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23955824" @default.
- W1566200162 hasPublicationYear "2012" @default.
- W1566200162 type Work @default.
- W1566200162 sameAs 1566200162 @default.
- W1566200162 citedByCount "12" @default.
- W1566200162 countsByYear W15662001622013 @default.
- W1566200162 countsByYear W15662001622014 @default.
- W1566200162 countsByYear W15662001622015 @default.
- W1566200162 countsByYear W15662001622016 @default.
- W1566200162 countsByYear W15662001622017 @default.
- W1566200162 countsByYear W15662001622018 @default.