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- W1566205281 abstract "Genomic tools have been developed to allow Emiliania huxleyi to be exploited as a full-featured model for investigating fundamental aspects of coccolithophore biology. To this end, large-scale expressed sequence tag programs have been undertaken and microarrays created with significant gene coverage to unravel one of the most important aspects of coccolithophore biology: that of the genes and proteins involved in calcification and coccolithogenesis. Investigations have also begun functionally to characterize some of the most interesting candidate bio-mineralization transcripts. The analyses to date indicate that biomineralization involves a variety of cellular processes, including cellular metabolism, ion transport, vesicular trafficking, lipid and polysaccharide synthesis, and cell signaling. The complex genetics and cellular physiology of biomineralization is unlikely to be explained by any one gene. To this end, these studies represent a first attempt to define the multiple interactions that characterize this complex process. Further systematic genome wide (and later, proteomic) analyses, in concert with detailed analysis of candidate proteins, will provide new connections between biomineralization and related cellular events that cannot be predicted with the very limited knowledge available at present." @default.
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- W1566205281 date "2007-05-25" @default.
- W1566205281 modified "2023-10-09" @default.
- W1566205281 title "Molecular Approaches to Emiliana huxleyi Coccolith Formation" @default.
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- W1566205281 doi "https://doi.org/10.1002/9783527619443.ch13" @default.
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