Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566270246> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W1566270246 abstract "Our previous research has demonstrated hyperinsulinemia and elevated lipogenesis by feeding pigs and rats with Se at 3.0 mg/kg of diet. This study was to determine the impacts of a moderately high Se (1.0 vs. 0.3 mg/kg as selenite) and(or) high fat (60 vs. 16% energy from fat) on lipid profiles in plasma, adipose and liver tissues of young adult (2-4 mo of age) and old (6-10 mo of age) wild-type (WT) and GPX1-/- (KO) male mice. A total of 80 mice were divided into 4 parallel (genotype by age) experiments (n = 5/group) and fed one of 4 diets for 6 wk. Body weight was elevated (P < 0.05) by the high fat diet in old WT and young KO mice, but decreased by high Se diet (P < 0.05) in young WT mice. Both high fat and Se intakes enhanced (P < 0.05) plasma glucose concentrations in old WT mice. High Se intake decreased plasma non-esterified fatty acids (NEFA) concentrations in young WT mice. There was little effect of high fat or Se intake on plasma lipid profiles of KO mice. Adipose tissue concentrations of triglycerides, cholesterol, and NEFA were consistently elevated by high fat and Se in both young WT and KO mice. In comparison, such effects of the dietary treatments on adipose tissue of old WT and KO mice or on liver of all 4 groups of mice were less obvious or consistent. In conclusion, our results revealed a uniquely high response of adipose tissue lipid profile to dietary intakes of high fat and Se and a strong interaction of age by GPX1 knockout on the response (NIH DK 53018). Grant Funding Source: (NIH DK 53018)." @default.
- W1566270246 created "2016-06-24" @default.
- W1566270246 creator A5016526933 @default.
- W1566270246 creator A5083905513 @default.
- W1566270246 creator A5091823146 @default.
- W1566270246 date "2014-04-01" @default.
- W1566270246 modified "2023-09-27" @default.
- W1566270246 title "Differential impacts of high fat and high Se diets on tissue lipid profiles of young adult and old wild‐type and GPX1‐/‐ mice (374.5)" @default.
- W1566270246 doi "https://doi.org/10.1096/fasebj.28.1_supplement.374.5" @default.
- W1566270246 hasPublicationYear "2014" @default.
- W1566270246 type Work @default.
- W1566270246 sameAs 1566270246 @default.
- W1566270246 citedByCount "0" @default.
- W1566270246 crossrefType "journal-article" @default.
- W1566270246 hasAuthorship W1566270246A5016526933 @default.
- W1566270246 hasAuthorship W1566270246A5083905513 @default.
- W1566270246 hasAuthorship W1566270246A5091823146 @default.
- W1566270246 hasBestOaLocation W15662702461 @default.
- W1566270246 hasConcept C126322002 @default.
- W1566270246 hasConcept C134018914 @default.
- W1566270246 hasConcept C141359234 @default.
- W1566270246 hasConcept C171089720 @default.
- W1566270246 hasConcept C185592680 @default.
- W1566270246 hasConcept C2777391703 @default.
- W1566270246 hasConcept C2779306644 @default.
- W1566270246 hasConcept C2779772378 @default.
- W1566270246 hasConcept C2780988686 @default.
- W1566270246 hasConcept C511355011 @default.
- W1566270246 hasConcept C71924100 @default.
- W1566270246 hasConcept C86803240 @default.
- W1566270246 hasConceptScore W1566270246C126322002 @default.
- W1566270246 hasConceptScore W1566270246C134018914 @default.
- W1566270246 hasConceptScore W1566270246C141359234 @default.
- W1566270246 hasConceptScore W1566270246C171089720 @default.
- W1566270246 hasConceptScore W1566270246C185592680 @default.
- W1566270246 hasConceptScore W1566270246C2777391703 @default.
- W1566270246 hasConceptScore W1566270246C2779306644 @default.
- W1566270246 hasConceptScore W1566270246C2779772378 @default.
- W1566270246 hasConceptScore W1566270246C2780988686 @default.
- W1566270246 hasConceptScore W1566270246C511355011 @default.
- W1566270246 hasConceptScore W1566270246C71924100 @default.
- W1566270246 hasConceptScore W1566270246C86803240 @default.
- W1566270246 hasFunder F4320332161 @default.
- W1566270246 hasIssue "S1" @default.
- W1566270246 hasLocation W15662702461 @default.
- W1566270246 hasOpenAccess W1566270246 @default.
- W1566270246 hasPrimaryLocation W15662702461 @default.
- W1566270246 hasRelatedWork W1592691368 @default.
- W1566270246 hasRelatedWork W1951732046 @default.
- W1566270246 hasRelatedWork W1957106181 @default.
- W1566270246 hasRelatedWork W1972831620 @default.
- W1566270246 hasRelatedWork W2066062695 @default.
- W1566270246 hasRelatedWork W2078141101 @default.
- W1566270246 hasRelatedWork W2104696040 @default.
- W1566270246 hasRelatedWork W2115594989 @default.
- W1566270246 hasRelatedWork W2284164753 @default.
- W1566270246 hasRelatedWork W2418477285 @default.
- W1566270246 hasVolume "28" @default.
- W1566270246 isParatext "false" @default.
- W1566270246 isRetracted "false" @default.
- W1566270246 magId "1566270246" @default.
- W1566270246 workType "article" @default.