Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566331025> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W1566331025 abstract "BACKGROUND & OBJECTIVE: White matter hyperintensities (WMH) indicate an increased risk of cerebrovascular events. Echocardiographic left ventricular hypertrophy (LVH) is an independent predictor of cardiovascular morbidity. We aimed to investigate the association between higher left ventricular mass index (LVMI) and severity of WMH in acute ischemic stroke. METHODS: We evaluated 868 consecutive acute ischemic stroke or transient ischemic attack (TIA) patients who were admitted within 7 days after onset of stroke and underwent magnetic resonance imaging (MRI) and transthoracic echocardiography. LVH was defined as a left ventricular mass index (LVMI) of > 115 g/m2 for men and > 95 g/m2 for women. Periventricular and deep white matter hyperintensities were systematically analyzed and rated according to the modified Fazekas scale (grade 0, 1, 2, and 3) on the baseline MRI. RESULTS: A total of 841 patients were included in this analysis. Numbers of WMH patients are 66 (7%) in grade 0, 546 (65%) in grade 1, 159 (20%) in grade 2, and 70 (8%) in grade 3. Mean LVMIs in each grade of WMH are 86 (SD 18) in grade 0, 95 (SD 22) in grade I, 104 (SD 29) in grade 2, and 100 (SD 28) in grade 3. LVH and 4th quartile of LVMI were associated with grade 2 (OR 2.3, 95% CI 1.1 to 5.0 and OR 3.2, 95% CI 1.4 to 7.2) and grade 3 (OR 2.5, 95% CI 1.1 to 5.9 and OR 2.7, 95% CI 1.1 to 6.6). Binary logistic regression analysis (WMH grade 0-1 versus grade 2-3) showed that age per year (OR 1.09, 95% CI 1.07 to 1.12, p<0.001), hypertension (OR 1.8, 95% CI 1.2 to 2.7, p=0.004), previous stroke or TIA history (OR 2.3, 95% CI 1.5 to 3.4, p<0.001) and increased LVMI per 10 g/m2 (OR 1.15; 95% CI 1.06 to 1.24, p<0.001) were independently associated with grade 2-3 WMH. CONCLUSIONS: Our results demonstrate that higher LVMI or LVH are independently associated with moderate to severe WMH in acute ischemic stroke and TIA patients even after adjusting of established cardiovascular risk factors. Further studies to evaluate whether regression of LVH slows the progression of WMH will be needed." @default.
- W1566331025 created "2016-06-24" @default.
- W1566331025 creator A5009323711 @default.
- W1566331025 creator A5019256390 @default.
- W1566331025 creator A5032333661 @default.
- W1566331025 creator A5077437724 @default.
- W1566331025 date "2015-02-01" @default.
- W1566331025 modified "2023-10-18" @default.
- W1566331025 title "Abstract W P184: Echocardiographic Left Ventricular Hypertrophy is Associated with Severity of Cerebral White Matter Hyperintensities in Acute Ischemic Stroke" @default.
- W1566331025 doi "https://doi.org/10.1161/str.46.suppl_1.wp184" @default.
- W1566331025 hasPublicationYear "2015" @default.
- W1566331025 type Work @default.
- W1566331025 sameAs 1566331025 @default.
- W1566331025 citedByCount "0" @default.
- W1566331025 crossrefType "journal-article" @default.
- W1566331025 hasAuthorship W1566331025A5009323711 @default.
- W1566331025 hasAuthorship W1566331025A5019256390 @default.
- W1566331025 hasAuthorship W1566331025A5032333661 @default.
- W1566331025 hasAuthorship W1566331025A5077437724 @default.
- W1566331025 hasConcept C126322002 @default.
- W1566331025 hasConcept C126838900 @default.
- W1566331025 hasConcept C127413603 @default.
- W1566331025 hasConcept C143409427 @default.
- W1566331025 hasConcept C146638467 @default.
- W1566331025 hasConcept C164705383 @default.
- W1566331025 hasConcept C2776002628 @default.
- W1566331025 hasConcept C2776191500 @default.
- W1566331025 hasConcept C2780645631 @default.
- W1566331025 hasConcept C44249647 @default.
- W1566331025 hasConcept C68443243 @default.
- W1566331025 hasConcept C71924100 @default.
- W1566331025 hasConcept C78519656 @default.
- W1566331025 hasConcept C84393581 @default.
- W1566331025 hasConceptScore W1566331025C126322002 @default.
- W1566331025 hasConceptScore W1566331025C126838900 @default.
- W1566331025 hasConceptScore W1566331025C127413603 @default.
- W1566331025 hasConceptScore W1566331025C143409427 @default.
- W1566331025 hasConceptScore W1566331025C146638467 @default.
- W1566331025 hasConceptScore W1566331025C164705383 @default.
- W1566331025 hasConceptScore W1566331025C2776002628 @default.
- W1566331025 hasConceptScore W1566331025C2776191500 @default.
- W1566331025 hasConceptScore W1566331025C2780645631 @default.
- W1566331025 hasConceptScore W1566331025C44249647 @default.
- W1566331025 hasConceptScore W1566331025C68443243 @default.
- W1566331025 hasConceptScore W1566331025C71924100 @default.
- W1566331025 hasConceptScore W1566331025C78519656 @default.
- W1566331025 hasConceptScore W1566331025C84393581 @default.
- W1566331025 hasIssue "suppl_1" @default.
- W1566331025 hasLocation W15663310251 @default.
- W1566331025 hasOpenAccess W1566331025 @default.
- W1566331025 hasPrimaryLocation W15663310251 @default.
- W1566331025 hasRelatedWork W1566331025 @default.
- W1566331025 hasRelatedWork W1989311450 @default.
- W1566331025 hasRelatedWork W1993468227 @default.
- W1566331025 hasRelatedWork W2034169195 @default.
- W1566331025 hasRelatedWork W2040809088 @default.
- W1566331025 hasRelatedWork W2814849521 @default.
- W1566331025 hasRelatedWork W2963525241 @default.
- W1566331025 hasRelatedWork W3032073674 @default.
- W1566331025 hasRelatedWork W3150917831 @default.
- W1566331025 hasRelatedWork W3213134665 @default.
- W1566331025 hasVolume "46" @default.
- W1566331025 isParatext "false" @default.
- W1566331025 isRetracted "false" @default.
- W1566331025 magId "1566331025" @default.
- W1566331025 workType "article" @default.