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- W1566331922 abstract "Research Article1 September 1992free access A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast. R. Gaxiola R. Gaxiola European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author I.F. de Larrinoa I.F. de Larrinoa European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author J.M. Villalba J.M. Villalba European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author R. Serrano R. Serrano European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author R. Gaxiola R. Gaxiola European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author I.F. de Larrinoa I.F. de Larrinoa European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author J.M. Villalba J.M. Villalba European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author R. Serrano R. Serrano European Molecular Biology Laboratory, Heidelberg, Germany. Search for more papers by this author Author Information R. Gaxiola1, I.F. Larrinoa1, J.M. Villalba1 and R. Serrano1 1European Molecular Biology Laboratory, Heidelberg, Germany. The EMBO Journal (1992)11:3157-3164https://doi.org/10.1002/j.1460-2075.1992.tb05392.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info We have isolated a novel yeast gene, HAL1, which upon overexpression improves growth under salt stress. In addition, disruption of this gene decreases salt tolerance. Therefore HAL1 constitutes a rate-limiting determinant for halotolerance. It encodes a polar protein of 32 kDa located in the yeast cytoplasm and unrelated to sequences in data banks. The expression of this gene is increased by high concentrations of either NaCl, KCl or sorbitol. On the other hand, the growth advantage obtained by overexpression of HAL1 is specific for NaCl stress. In cells overexpressing HAL1, sodium toxicity seems to be counteracted by an increased accumulation of potassium. The HAL1 protein could interact with the transport systems which determine intracellular K+ homeostasis. The HAL1 gene and encoded protein are conserved in plants, being induced in these organisms by salt stress and abscisic acid. These results suggest that yeast serves as a convenient model system for the molecular biology of plant salt tolerance. Previous ArticleNext Article Volume 11Issue 91 September 1992In this issue RelatedDetailsLoading ..." @default.
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- W1566331922 title "A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast." @default.
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- W1566331922 doi "https://doi.org/10.1002/j.1460-2075.1992.tb05392.x" @default.
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