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- W1566374197 abstract "Fertilised eggs of Xenopus laevis were injected with rabbit or mouse globin mRNA and allowed to develop. At various times after hatching they were dissected and different regions incubated with radioactive histidine. Two main regions were studied: the yolky endoderm plus ventral mesoderm, and the axial region containing functional myotomes, nerve cord, and notochord. Both regions synthesized the globin appropriate to the source of the injected mRNA and globin synthesis represented a similar proportion of total protein synthesis in each part. The ratio of α to β globin synthesis was not affected by the region of the embryo in which injected mRNA was translated. We conclude that the injected mRNA was evenly distributed in the developing embryos and was translated efficiently in differentiating tissues with no erythropoietic function." @default.
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- W1566374197 date "1974-07-01" @default.
- W1566374197 modified "2023-10-14" @default.
- W1566374197 title "The translation of mammalian globin mRNA injected into fertilised eggs of Xenopus laevis" @default.
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- W1566374197 doi "https://doi.org/10.1016/s0012-1606(74)80015-1" @default.
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