FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566565565> ?p ?o ?g. }

• W1566565565 endingPage "679" @default.
• W1566565565 startingPage "675" @default.
• W1566565565 abstract "Growth of Escherichia coli on acetate requires operation of the anaplerotic sequence known as the glyoxylate bypass. In this pathway three different enzymes are activated: malate synthase, isocitrate lyase and isocitrate dehydrogenase kinase/phosphatase which are encoded by genes aceB, aceA and aceK, respectively. These three genes are clustered, in that order, in the same acetate (ace) operon whose expression is under the transcriptional control of the iclR gene located downstream from aceK. We have cloned the iclR gene in the pKK233-2 vector which allows optimization of both transcription and translation initiation. The IclR repressor has been overproduced, then purified to homogeneity in a one-step procedure by cation exchange chromatography after ammonium sulfate fractionation. Its specific interaction with the operator/promoter region of the ace operon has been analyzed by gel retardation and DNase I footprinting experiments. The IclR repressor has been shown to recognize a 35 bp palindromic sequence which largely overlaps the -35 recognition site of RNA polymerase. Moreover, the formation of the complex between IclR and the operator/promoter region has been found to be impaired by phosphoenol pyruvate but insensitive to acetate, acetyl-CoA, pyruvate, and oxaloacetate. These results are discussed in terms of primary regulation of the expression of the ace operon." @default.
• W1566565565 created "2016-06-24" @default.
• W1566565565 creator A5004975943 @default.
• W1566565565 creator A5005054796 @default.
• W1566565565 creator A5013133004 @default.
• W1566565565 creator A5052837496 @default.
• W1566565565 creator A5086710169 @default.
• W1566565565 creator A5087824553 @default.
• W1566565565 date "1991-03-01" @default.
• W1566565565 modified "2023-10-16" @default.
• W1566565565 title "Regulation of the acetate operon in Escherichia coli: purification and functional characterization of the IclR repressor." @default.
• W1566565565 cites W1480025162 @default.
• W1566565565 cites W1543086202 @default.
• W1566565565 cites W1555898673 @default.
• W1566565565 cites W1570124823 @default.
• W1566565565 cites W1598056778 @default.
• W1566565565 cites W1611419319 @default.
• W1566565565 cites W1687960050 @default.
• W1566565565 cites W1736027806 @default.
• W1566565565 cites W1825429543 @default.
• W1566565565 cites W186483356 @default.
• W1566565565 cites W1901024895 @default.
• W1566565565 cites W1908308709 @default.
• W1566565565 cites W1952814327 @default.
• W1566565565 cites W1965267927 @default.
• W1566565565 cites W1989080074 @default.
• W1566565565 cites W2004563262 @default.
• W1566565565 cites W2028701325 @default.
• W1566565565 cites W2032118018 @default.
• W1566565565 cites W2049105193 @default.
• W1566565565 cites W2056277832 @default.
• W1566565565 cites W2059918776 @default.
• W1566565565 cites W2078731027 @default.
• W1566565565 cites W2088635713 @default.
• W1566565565 cites W2095020505 @default.
• W1566565565 cites W2128635872 @default.
• W1566565565 cites W2157387173 @default.
• W1566565565 cites W2245249207 @default.
• W1566565565 doi "https://doi.org/10.1002/j.1460-2075.1991.tb07996.x" @default.
• W1566565565 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/452701" @default.
• W1566565565 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2001680" @default.
• W1566565565 hasPublicationYear "1991" @default.
• W1566565565 type Work @default.
• W1566565565 sameAs 1566565565 @default.
• W1566565565 citedByCount "77" @default.
• W1566565565 countsByYear W15665655652012 @default.
• W1566565565 countsByYear W15665655652013 @default.
• W1566565565 countsByYear W15665655652014 @default.
• W1566565565 countsByYear W15665655652015 @default.
• W1566565565 countsByYear W15665655652016 @default.
• W1566565565 countsByYear W15665655652017 @default.
• W1566565565 countsByYear W15665655652018 @default.
• W1566565565 countsByYear W15665655652019 @default.
• W1566565565 countsByYear W15665655652020 @default.
• W1566565565 countsByYear W15665655652021 @default.
• W1566565565 countsByYear W15665655652023 @default.
• W1566565565 crossrefType "journal-article" @default.
• W1566565565 hasAuthorship W1566565565A5004975943 @default.
• W1566565565 hasAuthorship W1566565565A5005054796 @default.
• W1566565565 hasAuthorship W1566565565A5013133004 @default.
• W1566565565 hasAuthorship W1566565565A5052837496 @default.
• W1566565565 hasAuthorship W1566565565A5086710169 @default.
• W1566565565 hasAuthorship W1566565565A5087824553 @default.
• W1566565565 hasBestOaLocation W15665655654 @default.
• W1566565565 hasConcept C104317684 @default.
• W1566565565 hasConcept C150194340 @default.
• W1566565565 hasConcept C153911025 @default.
• W1566565565 hasConcept C158448853 @default.
• W1566565565 hasConcept C165267168 @default.
• W1566565565 hasConcept C170344550 @default.
• W1566565565 hasConcept C181199279 @default.
• W1566565565 hasConcept C203075996 @default.
• W1566565565 hasConcept C2776336597 @default.
• W1566565565 hasConcept C2779969133 @default.
• W1566565565 hasConcept C37150987 @default.
• W1566565565 hasConcept C547475151 @default.
• W1566565565 hasConcept C55493867 @default.
• W1566565565 hasConcept C69953675 @default.
• W1566565565 hasConcept C86803240 @default.
• W1566565565 hasConceptScore W1566565565C104317684 @default.
• W1566565565 hasConceptScore W1566565565C150194340 @default.
• W1566565565 hasConceptScore W1566565565C153911025 @default.
• W1566565565 hasConceptScore W1566565565C158448853 @default.
• W1566565565 hasConceptScore W1566565565C165267168 @default.
• W1566565565 hasConceptScore W1566565565C170344550 @default.
• W1566565565 hasConceptScore W1566565565C181199279 @default.
• W1566565565 hasConceptScore W1566565565C203075996 @default.
• W1566565565 hasConceptScore W1566565565C2776336597 @default.
• W1566565565 hasConceptScore W1566565565C2779969133 @default.
• W1566565565 hasConceptScore W1566565565C37150987 @default.
• W1566565565 hasConceptScore W1566565565C547475151 @default.
• W1566565565 hasConceptScore W1566565565C55493867 @default.
• W1566565565 hasConceptScore W1566565565C69953675 @default.
• W1566565565 hasConceptScore W1566565565C86803240 @default.
• W1566565565 hasIssue "3" @default.
• W1566565565 hasLocation W15665655651 @default.
• W1566565565 hasLocation W15665655652 @default.
• W1566565565 hasLocation W15665655653 @default.

• next