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- W1566576992 abstract "A practical and economical process for the synthesis of perfluoroalkylated indole compounds has been developed. The Michael addition of 2-iodo- or 2-bromoanilines to methyl perfluoroalk-2-ynoates affords N-(o-haloaryl)enamines, which subsequently undergo a copper-catalyzed annulation reaction to give 2-perfluoroalkyl-substituted indoles in good to excellent yields. This method displays excellent functional group tolerance and is carried out in one pot under mild conditions." @default.
- W1566576992 created "2016-06-24" @default.
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- W1566576992 date "2014-03-13" @default.
- W1566576992 modified "2023-10-07" @default.
- W1566576992 title "Facile Synthesis of 2-(Perfluoroalkyl)indoles through a Michael Addition/Cu<sup>I</sup>-Catalyzed Annulation Process" @default.
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- W1566576992 doi "https://doi.org/10.1002/ejoc.201400056" @default.
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