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- W1566579330 abstract "The 10-year survival rate for patients with metastatic melanoma is less than 10%. Although surgery and radiation therapy have a role in the treatment of metastatic disease, systemic therapy is the mainstay of treatment for most patients. Single-agent chemotherapy is well tolerated but is associated with response rates of only 5% to 20%. Combination chemotherapy and biochemotherapy may improve objective response rates but do not extend survival and are associated with greater toxicity. Immunotherapeutic approaches such as high-dose interleukin-2 are associated with durable responses in a small percentage of patients. In this article, we review the treatments for metastatic melanoma including promising investigational approaches." @default.
- W1566579330 created "2016-06-24" @default.
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- W1566579330 date "2009-05-01" @default.
- W1566579330 modified "2023-10-10" @default.
- W1566579330 title "Treatment of metastatic melanoma: an overview." @default.
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