Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566609868> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1566609868 endingPage "6" @default.
- W1566609868 startingPage "532" @default.
- W1566609868 abstract "The in vitro incorporation of formate-C14 into the protein and lipids of several leukemic mouse tissues and of normal mouse liver has been studied. The folic acid analog, A-methopterin, has been shown to inhibit by 72 per cent the incorporation of formate-C14 into the protein of leukemic cells sensitive in vivo to A-methopterin. A-methopterin inhibited by 40 per cent the incorporation of the isotope into the proteins of a lymphoma resistant in vivo to A-methopterin therapy. There was no significant effect of A-methopterin on the incorporation of formate-C14 into the gross protein fraction of normal mouse liver.The protein residue from the L1210-S lymphoma incubated in the presence and absence of A-methopterin was further fractionated to isolated pure methionine, serine, adenine, and guanine. Serine had the highest specific activity, with the purines having about 40 per cent as much activity as serine, and methionine about one-third of the activity of the purines. The inhibitory effect of A-methopterin on the incorporation of formate-C14 into ribonucleic acid purines was significantly greater than its effect on incorporation into serine and methionine." @default.
- W1566609868 created "2016-06-24" @default.
- W1566609868 creator A5013137140 @default.
- W1566609868 creator A5067037565 @default.
- W1566609868 creator A5087267135 @default.
- W1566609868 date "1955-09-01" @default.
- W1566609868 modified "2023-09-23" @default.
- W1566609868 title "The effect of A-methopterin on formate-C14 incorporation by mouse leukemias in vitro." @default.
- W1566609868 cites W1508265353 @default.
- W1566609868 cites W1514995876 @default.
- W1566609868 cites W1545824734 @default.
- W1566609868 cites W1549825490 @default.
- W1566609868 cites W1550440225 @default.
- W1566609868 cites W1603759750 @default.
- W1566609868 cites W1629330579 @default.
- W1566609868 cites W1872568885 @default.
- W1566609868 cites W1980718269 @default.
- W1566609868 cites W2061654971 @default.
- W1566609868 cites W2190682472 @default.
- W1566609868 cites W2285934889 @default.
- W1566609868 cites W2325452926 @default.
- W1566609868 cites W2328999771 @default.
- W1566609868 cites W2412546286 @default.
- W1566609868 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13250519" @default.
- W1566609868 hasPublicationYear "1955" @default.
- W1566609868 type Work @default.
- W1566609868 sameAs 1566609868 @default.
- W1566609868 citedByCount "5" @default.
- W1566609868 crossrefType "journal-article" @default.
- W1566609868 hasAuthorship W1566609868A5013137140 @default.
- W1566609868 hasAuthorship W1566609868A5067037565 @default.
- W1566609868 hasAuthorship W1566609868A5087267135 @default.
- W1566609868 hasConcept C104317684 @default.
- W1566609868 hasConcept C11960822 @default.
- W1566609868 hasConcept C150903083 @default.
- W1566609868 hasConcept C153911025 @default.
- W1566609868 hasConcept C161790260 @default.
- W1566609868 hasConcept C169586020 @default.
- W1566609868 hasConcept C181199279 @default.
- W1566609868 hasConcept C185592680 @default.
- W1566609868 hasConcept C202751555 @default.
- W1566609868 hasConcept C207001950 @default.
- W1566609868 hasConcept C2776414213 @default.
- W1566609868 hasConcept C2776476023 @default.
- W1566609868 hasConcept C2777756961 @default.
- W1566609868 hasConcept C2778301229 @default.
- W1566609868 hasConcept C2780178953 @default.
- W1566609868 hasConcept C2780912031 @default.
- W1566609868 hasConcept C512185932 @default.
- W1566609868 hasConcept C515207424 @default.
- W1566609868 hasConcept C55493867 @default.
- W1566609868 hasConcept C62231903 @default.
- W1566609868 hasConcept C86803240 @default.
- W1566609868 hasConceptScore W1566609868C104317684 @default.
- W1566609868 hasConceptScore W1566609868C11960822 @default.
- W1566609868 hasConceptScore W1566609868C150903083 @default.
- W1566609868 hasConceptScore W1566609868C153911025 @default.
- W1566609868 hasConceptScore W1566609868C161790260 @default.
- W1566609868 hasConceptScore W1566609868C169586020 @default.
- W1566609868 hasConceptScore W1566609868C181199279 @default.
- W1566609868 hasConceptScore W1566609868C185592680 @default.
- W1566609868 hasConceptScore W1566609868C202751555 @default.
- W1566609868 hasConceptScore W1566609868C207001950 @default.
- W1566609868 hasConceptScore W1566609868C2776414213 @default.
- W1566609868 hasConceptScore W1566609868C2776476023 @default.
- W1566609868 hasConceptScore W1566609868C2777756961 @default.
- W1566609868 hasConceptScore W1566609868C2778301229 @default.
- W1566609868 hasConceptScore W1566609868C2780178953 @default.
- W1566609868 hasConceptScore W1566609868C2780912031 @default.
- W1566609868 hasConceptScore W1566609868C512185932 @default.
- W1566609868 hasConceptScore W1566609868C515207424 @default.
- W1566609868 hasConceptScore W1566609868C55493867 @default.
- W1566609868 hasConceptScore W1566609868C62231903 @default.
- W1566609868 hasConceptScore W1566609868C86803240 @default.
- W1566609868 hasIssue "8" @default.
- W1566609868 hasLocation W15666098681 @default.
- W1566609868 hasOpenAccess W1566609868 @default.
- W1566609868 hasPrimaryLocation W15666098681 @default.
- W1566609868 hasRelatedWork W1566609868 @default.
- W1566609868 hasRelatedWork W1572345716 @default.
- W1566609868 hasRelatedWork W1818819312 @default.
- W1566609868 hasRelatedWork W1834167336 @default.
- W1566609868 hasRelatedWork W1852981991 @default.
- W1566609868 hasRelatedWork W1966774674 @default.
- W1566609868 hasRelatedWork W2056620759 @default.
- W1566609868 hasRelatedWork W2154050725 @default.
- W1566609868 hasRelatedWork W272797503 @default.
- W1566609868 hasRelatedWork W756165753 @default.
- W1566609868 hasVolume "15" @default.
- W1566609868 isParatext "false" @default.
- W1566609868 isRetracted "false" @default.
- W1566609868 magId "1566609868" @default.
- W1566609868 workType "article" @default.