Matches in SemOpenAlex for { <https://semopenalex.org/work/W1566681761> ?p ?o ?g. }
- W1566681761 endingPage "1063" @default.
- W1566681761 startingPage "1051" @default.
- W1566681761 abstract "Diabetes mellitus is characterized by hyperglycemia and a range of associated metabolic changes which promote the development of inflammatory thrombotic abnormalities that contribute to vascular damage. Inhibition of fibrinolysis due to elevated levels of plasminogen activator inhibitor-1 is a core feature of insulin resistance, and hyperglycemia further contributes by generating a fibrin structure resistant to lysis. The platelet responds to diabetes by increasing aggregation and adhesion and by interacting with inflammatory cells to promote an inflammatory/thrombotic environment. Complex inflammatory/thrombotic interactions drive the abnormalities in thrombosis seen in diabetes and disturbances in circadian rhythms may provide the link between obesity, insulin resistance, and thrombotic risk. Management of insulin resistance and hyperglycemia has beneficial effects on the prothrombotic profile in diabetes by enhancing clot lysis and reducing platelet activation." @default.
- W1566681761 created "2016-06-24" @default.
- W1566681761 creator A5036249431 @default.
- W1566681761 creator A5086223086 @default.
- W1566681761 date "2015-03-06" @default.
- W1566681761 modified "2023-10-16" @default.
- W1566681761 title "Hemostatic abnormalities in diabetes mellitus" @default.
- W1566681761 cites W107577559 @default.
- W1566681761 cites W1519150396 @default.
- W1566681761 cites W1903216452 @default.
- W1566681761 cites W1951511885 @default.
- W1566681761 cites W1969822121 @default.
- W1566681761 cites W1970328528 @default.
- W1566681761 cites W1983973011 @default.
- W1566681761 cites W1984973899 @default.
- W1566681761 cites W1987637100 @default.
- W1566681761 cites W1991097075 @default.
- W1566681761 cites W1991655882 @default.
- W1566681761 cites W1993975599 @default.
- W1566681761 cites W1996333896 @default.
- W1566681761 cites W2001688139 @default.
- W1566681761 cites W2005998137 @default.
- W1566681761 cites W2007158657 @default.
- W1566681761 cites W2007499677 @default.
- W1566681761 cites W2007725602 @default.
- W1566681761 cites W2011854883 @default.
- W1566681761 cites W2012818276 @default.
- W1566681761 cites W2014625989 @default.
- W1566681761 cites W2015175766 @default.
- W1566681761 cites W2018383335 @default.
- W1566681761 cites W2018651068 @default.
- W1566681761 cites W2019631323 @default.
- W1566681761 cites W2021754558 @default.
- W1566681761 cites W2022036486 @default.
- W1566681761 cites W2023758763 @default.
- W1566681761 cites W2023940184 @default.
- W1566681761 cites W2024352468 @default.
- W1566681761 cites W2025462550 @default.
- W1566681761 cites W2029684068 @default.
- W1566681761 cites W2033055236 @default.
- W1566681761 cites W2034942998 @default.
- W1566681761 cites W2039483820 @default.
- W1566681761 cites W2040227938 @default.
- W1566681761 cites W2044660277 @default.
- W1566681761 cites W2045970079 @default.
- W1566681761 cites W2046971159 @default.
- W1566681761 cites W2049166597 @default.
- W1566681761 cites W2049701863 @default.
- W1566681761 cites W2050820265 @default.
- W1566681761 cites W2052419530 @default.
- W1566681761 cites W2053216233 @default.
- W1566681761 cites W2053379248 @default.
- W1566681761 cites W2055270617 @default.
- W1566681761 cites W2058738527 @default.
- W1566681761 cites W2064289147 @default.
- W1566681761 cites W2068787504 @default.
- W1566681761 cites W2069286302 @default.
- W1566681761 cites W2072349497 @default.
- W1566681761 cites W2081799397 @default.
- W1566681761 cites W2084673482 @default.
- W1566681761 cites W2086493066 @default.
- W1566681761 cites W2087951913 @default.
- W1566681761 cites W2089218123 @default.
- W1566681761 cites W2089548328 @default.
- W1566681761 cites W2091234741 @default.
- W1566681761 cites W2092063558 @default.
- W1566681761 cites W2096744115 @default.
- W1566681761 cites W2100771558 @default.
- W1566681761 cites W2104599604 @default.
- W1566681761 cites W2105881737 @default.
- W1566681761 cites W2107797912 @default.
- W1566681761 cites W2113510279 @default.
- W1566681761 cites W2114389657 @default.
- W1566681761 cites W2115340622 @default.
- W1566681761 cites W2120071870 @default.
- W1566681761 cites W2120303579 @default.
- W1566681761 cites W2123973590 @default.
- W1566681761 cites W2125326676 @default.
- W1566681761 cites W2127304691 @default.
- W1566681761 cites W2128420611 @default.
- W1566681761 cites W2128715802 @default.
- W1566681761 cites W2131184211 @default.
- W1566681761 cites W2140678750 @default.
- W1566681761 cites W2141030542 @default.
- W1566681761 cites W2145306055 @default.
- W1566681761 cites W2149745129 @default.
- W1566681761 cites W2153915623 @default.
- W1566681761 cites W2161844490 @default.
- W1566681761 cites W2163986031 @default.
- W1566681761 cites W2167095513 @default.
- W1566681761 cites W2169387542 @default.
- W1566681761 cites W2169952624 @default.
- W1566681761 cites W2171232249 @default.
- W1566681761 cites W2232912109 @default.
- W1566681761 cites W2316166446 @default.
- W1566681761 cites W2316759486 @default.
- W1566681761 cites W2317366912 @default.
- W1566681761 cites W2325460018 @default.