Matches in SemOpenAlex for { <https://semopenalex.org/work/W156668648> ?p ?o ?g. }
- W156668648 endingPage "427" @default.
- W156668648 startingPage "423" @default.
- W156668648 abstract "The pathophysiology of spontaneous abortion is complex and may involve the interaction of genetic and environmental factors. We evaluated the predictors of spontaneous abortion in Brazilian pregnant women. The effects of age, gestational age, body mass index (BMI), cigarette smoking, alcohol ingestion, use of multivitamins and concentrations of vitamins (folate, cobalamin and vitamin B6) and vitamin-dependent metabolites were analyzed. Study population included 100 healthy women that attended pre-natal care in 2 health centers of Sao Paulo, Brazil, and in whom pregnancy outcome was known. Folate and cobalamin status was measured in blood specimens collected between 4 and 16 weeks. The genotypes for 8 gene polymorphisms were evaluated by PCR-RFLP. Eighty-eight women had normal pregnancy outcome (Group 1), while 12 experienced a miscarriage after blood collection (Group 2). Increased methylmalonic acid (MMA) concentrations were found in Group 2 (median [25th–75th percentile] = 274 [149–425] nmol/l) relative to Group 1 (138 [98–185]) (P < 0.01). No differences between the groups were observed for serum cobalamin, serum or red cell folate, and serum total homocysteine or allele frequencies for 8 polymorphisms. In a conditional logistic regression analysis including age, gestational age, serum creatinine, MMA, cystathionine, body mass index (BMI), cigarette smoking, alcohol ingestion and use of multivitamins the risk of abortion was significantly associated with MMA (OR [95% CI] = 3.80 [1.36, 10.62] per quartile increase in MMA), BMI (OR [95% CI] = 5.49 [1.29, 23.39] per quartile) and gestational age (OR [95% CI] = 0.10 [0.01, 0.77] per increase of interval in gestational age). Increased serum MMA and BMI concentrations are associated with spontaneous abortion in Brazilian women." @default.
- W156668648 created "2016-06-24" @default.
- W156668648 creator A5006536538 @default.
- W156668648 creator A5013709045 @default.
- W156668648 creator A5017751778 @default.
- W156668648 creator A5030872957 @default.
- W156668648 creator A5056688129 @default.
- W156668648 creator A5056996183 @default.
- W156668648 creator A5069127802 @default.
- W156668648 creator A5078674989 @default.
- W156668648 creator A5086312485 @default.
- W156668648 date "2010-03-01" @default.
- W156668648 modified "2023-10-01" @default.
- W156668648 title "Increased MMA concentration and body mass index are associated with spontaneous abortion in Brazilian women" @default.
- W156668648 cites W1566423811 @default.
- W156668648 cites W1620461659 @default.
- W156668648 cites W1874911532 @default.
- W156668648 cites W1883635241 @default.
- W156668648 cites W1971495699 @default.
- W156668648 cites W1992651294 @default.
- W156668648 cites W2005228342 @default.
- W156668648 cites W2022236323 @default.
- W156668648 cites W2025547051 @default.
- W156668648 cites W2030041438 @default.
- W156668648 cites W2031262735 @default.
- W156668648 cites W2037748478 @default.
- W156668648 cites W2041886881 @default.
- W156668648 cites W2041995978 @default.
- W156668648 cites W2048969389 @default.
- W156668648 cites W2069196865 @default.
- W156668648 cites W2078453735 @default.
- W156668648 cites W2085328480 @default.
- W156668648 cites W2090474126 @default.
- W156668648 cites W2097196943 @default.
- W156668648 cites W2097412489 @default.
- W156668648 cites W2112839082 @default.
- W156668648 cites W2120936829 @default.
- W156668648 cites W2150122989 @default.
- W156668648 cites W2151172455 @default.
- W156668648 cites W2151615720 @default.
- W156668648 cites W2153804701 @default.
- W156668648 cites W2154720911 @default.
- W156668648 cites W2161625263 @default.
- W156668648 cites W2165715420 @default.
- W156668648 cites W2167483536 @default.
- W156668648 cites W2170134708 @default.
- W156668648 cites W2319182210 @default.
- W156668648 cites W2413759248 @default.
- W156668648 cites W4246134835 @default.
- W156668648 doi "https://doi.org/10.1016/j.cca.2009.12.014" @default.
- W156668648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20036223" @default.
- W156668648 hasPublicationYear "2010" @default.
- W156668648 type Work @default.
- W156668648 sameAs 156668648 @default.
- W156668648 citedByCount "10" @default.
- W156668648 countsByYear W1566686482012 @default.
- W156668648 countsByYear W1566686482013 @default.
- W156668648 countsByYear W1566686482014 @default.
- W156668648 countsByYear W1566686482016 @default.
- W156668648 countsByYear W1566686482017 @default.
- W156668648 countsByYear W1566686482019 @default.
- W156668648 countsByYear W1566686482020 @default.
- W156668648 countsByYear W1566686482021 @default.
- W156668648 crossrefType "journal-article" @default.
- W156668648 hasAuthorship W156668648A5006536538 @default.
- W156668648 hasAuthorship W156668648A5013709045 @default.
- W156668648 hasAuthorship W156668648A5017751778 @default.
- W156668648 hasAuthorship W156668648A5030872957 @default.
- W156668648 hasAuthorship W156668648A5056688129 @default.
- W156668648 hasAuthorship W156668648A5056996183 @default.
- W156668648 hasAuthorship W156668648A5069127802 @default.
- W156668648 hasAuthorship W156668648A5078674989 @default.
- W156668648 hasAuthorship W156668648A5086312485 @default.
- W156668648 hasBestOaLocation W1566686481 @default.
- W156668648 hasConcept C126322002 @default.
- W156668648 hasConcept C131872663 @default.
- W156668648 hasConcept C2776551950 @default.
- W156668648 hasConcept C2776940978 @default.
- W156668648 hasConcept C2777090595 @default.
- W156668648 hasConcept C2778376644 @default.
- W156668648 hasConcept C2779234561 @default.
- W156668648 hasConcept C2779245376 @default.
- W156668648 hasConcept C2779750884 @default.
- W156668648 hasConcept C2779821038 @default.
- W156668648 hasConcept C2780221984 @default.
- W156668648 hasConcept C2780306776 @default.
- W156668648 hasConcept C2780676250 @default.
- W156668648 hasConcept C2908647359 @default.
- W156668648 hasConcept C42407357 @default.
- W156668648 hasConcept C54355233 @default.
- W156668648 hasConcept C71924100 @default.
- W156668648 hasConcept C86803240 @default.
- W156668648 hasConcept C90924648 @default.
- W156668648 hasConcept C99454951 @default.
- W156668648 hasConceptScore W156668648C126322002 @default.
- W156668648 hasConceptScore W156668648C131872663 @default.
- W156668648 hasConceptScore W156668648C2776551950 @default.
- W156668648 hasConceptScore W156668648C2776940978 @default.